ArticleCurrent eye research2013
Fundus camera guided photoacoustic ophthalmoscopy.
Article in Current eye research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Multimodal photoacoustic microscopy and optical coherence tomography ocular biomarker imaging in Alzheimer's disease in mice.Biomedical optics express · 2024Article
- Multiple Preprocessing Hybrid Level Set Model for Optic Disc Segmentation in Fundus Images.Sensors (Basel, Switzerland) · 2022Article
- Imaging the Retinal Vasculature.Annual review of vision science · 2021Review
- Gold Nanorod Enhanced Photoacoustic Microscopy and Optical Coherence Tomography of Choroidal Neovascularization.ACS applied materials & interfaces · 2021Article
- Advances in Retinal Oximetry.Translational vision science & technology · 2021Review
- Plasmonic Gold Nanostar-Enhanced Multimodal Photoacoustic Microscopy and Optical Coherence Tomography Molecular Imaging To Evaluate Choroidal Neovascularization.ACS sensors · 2020Article
- Feasibility Study of Precise Balloon Catheter Tracking and Visualization with Fast Photoacoustic Microscopy.Sensors (Basel, Switzerland) · 2020Article
- Contrast Agent Enhanced Multimodal Photoacoustic Microscopy and Optical Coherence Tomography for Imaging of Rabbit Choroidal and Retinal Vessels in vivo.Scientific reports · 2019Article
- Multi-wavelength, en-face photoacoustic microscopy and optical coherence tomography imaging for early and selective detection of laser induced retinal vein occlusion.Biomedical optics express · 2018Article
- Photoacoustic Ophthalmoscopy: Principle, Application, and Future Directions.Journal of imaging · 2018Article
- In Vivo 3D Imaging of Retinal Neovascularization Using Multimodal Photoacoustic Microscopy and Optical Coherence Tomography Imaging.Journal of imaging · 2018Article
- In vivo photoacoustic imaging of chorioretinal oxygen gradients.Journal of biomedical optics · 2018Article
- Imaging retinal melanin: a review of current technologies.Journal of biological engineering · 2018Review
- Snapshot hyperspectral retinal imaging using compact spectral resolving detector array.Journal of biophotonics · 2017Article
- Photoacoustic imaging of the eye: A mini review.Photoacoustics · 2016Review
- Tutorial on photoacoustic tomography.Journal of biomedical optics · 2016Review
- Fully motorized optical-resolution photoacoustic microscopy.Optics letters · 2014Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
purposeTo demonstrate the feasibility of fundus camera guided photoacoustic ophthalmoscopy (PAOM) system and its multimodal imaging capabilities.
methodsWe integrated PAOM and a fundus camera consisting of a white-light illuminator and a high-sensitivity, high-speed CCD. The fundus camera captures both retinal anatomy and PAOM illumination at the same time to provide a real-time feedback when we position the PAOM illuminating light. We applied the integrated system to image rat eyes in vivo and used full-spectrum, visible (VIS), and near infrared (NIR) illuminations in fundus photography.
resultsBoth albino and pigmented rat eyes were imaged in vivo. During alignment, different trajectories of PAOM laser scanning were successfully visualized by the fundus camera, which reduced the PAOM alignment time from several minutes to 30 s. In albino eyes, in addition to retinal vessels, main choroidal vessels were observed using VIS-illumination, which is similar to PAOM images. In pigmented eyes, the radial striations of retinal nerve fiber layer were visualized by fundus photography using full-spectrum illumination; meanwhile, PAOM imaged both retinal vessels and the retinal pigmented epithelium melanin distribution.
conclusionsThe results demonstrated that PAOM can be well-integrated with fundus camera without affecting its functionality. The fundus camera guidance is faster and easier comparing with our previous work. The integrated system also set the stage for the next-step verification between oximetry methods based on PAOM and fundus photography.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.