ArticlePloS one2013
Incidence and cost of pneumonia in older adults with COPD in the United States.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Excess costs of comorbidities in chronic obstructive pulmonary disease: a systematic review.PloS one · 2015Pooled it
- Chronic obstructive pulmonary disease treated with inhaled medium- or high-dose corticosteroids: a prospective and randomized study focusing on clinical efficacy and the risk of pneumonia.Drug design, development and therapy · 2014Trial
- Article
- Urban-rural differences in pneumonia risk in patients with chronic obstructive pulmonary disease: a nationwide register-based study.European clinical respiratory journal · 2025Article
- Hospital Admission Rates in Patients with COPD Throughout the COVID-19 Pandemic.International journal of chronic obstructive pulmonary disease · 2023Article
- Effectiveness and Safety of COPD Maintenance Therapy with Tiotropium/Olodaterol versus LABA/ICS in a US Claims Database.Advances in therapy · 2021Observational
- Real-world evaluation of costs of illness for pneumonia in adult patients in Dubai-A claims database study.PloS one · 2021Article
- Vaccine strategies for prevention of community-acquired pneumonia in Canada: Who would benefit most from pneumococcal immunization?Canadian family physician Medecin de famille canadien · 2019Review
- Patient-Reported Consequences of Community-Acquired Pneumonia in Patients with Chronic Obstructive Pulmonary Disease.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2019Article
- The mortality risk factor of community acquired pneumonia patients with chronic obstructive pulmonary disease: a retrospective cohort study.BMC pulmonary medicine · 2018Article
- Irradiation enhanced risks of hospitalised pneumonopathy in lung cancer patients: a population-based surgical cohort study.BMJ open · 2017Article
- Pneumococcal vaccination and chronic respiratory diseases.International journal of chronic obstructive pulmonary disease · 2017Review
- Risk of Stroke and Post-Stroke Adverse Events in Patients with Exacerbations of Chronic Obstructive Pulmonary Disease.PloS one · 2017Article
- Risk of community-acquired pneumonia in chronic obstructive pulmonary disease stratified by smoking status: a population-based cohort study in the United Kingdom.International journal of chronic obstructive pulmonary disease · 2017Article
- Cadmium attenuates the macrophage response to LPS through inhibition of the NF-κB pathway.American journal of physiology. Lung cellular and molecular physiology · 2016Article
- Community-acquired pneumonia and survival of critically ill acute exacerbation of COPD patients in respiratory intensive care units.International journal of chronic obstructive pulmonary disease · 2016Observational
- Incidence and outcomes of patients hospitalized with COPD exacerbation with and without pneumonia.International journal of chronic obstructive pulmonary disease · 2016Article
- Pneumococcal lower respiratory tract infections in adults: an observational case-control study in primary care in Belgium.BMC family practice · 2015Observational
- Validation of an administrative claims-based diagnostic code for pneumonia in a US-based commercially insured COPD population.International journal of chronic obstructive pulmonary disease · 2015Article
- Community-acquired pneumonia in patients with chronic obstructive pulmonary disease.Current infectious disease reports · 2015Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo estimate the incidence of pneumonia by COPD status and the excess cost of inpatient primary pneumonia in elders with COPD. STUDY
designA retrospective, longitudinal study using claims linked to eligibility/demographic data for a 5% sample of fee-for-service Medicare beneficiaries from 2005 through 2007.
methodsIncidence rates of pneumonia were calculated for elders with and without COPD and for elders with COPD and coexistent congestive heart failure (CHF). Propensity-score matching with multivariate generalized linear regression was used to estimate the excess direct medical cost of inpatient primary pneumonia in elders with COPD as compared with elders with COPD but without a pneumonia hospitalization.
resultsElders with COPD had nearly six-times the incidence of pneumonia compared with elders without COPD (167.6/1000 person-years versus 29.5/1000 person-years; RR=5.7, p <0 .01); RR increased to 8.1 for elders with COPD and CHF compared with elders without COPD. The incidence of inpatient primary pneumonia among elders with COPD was 54.2/1000 person-years compared with 7/1000 person-years for elders without COPD; RR=7.7, p<0.01); RR increased to 11.0 for elders with COPD and CHF compared with elders without COPD. The one-year excess direct medical cost of inpatient pneumonia in COPD patients was $ 22,697 ($45,456 in cases vs. $ 22,759 in controls (p <0.01)); 70.2% of this cost was accrued during the quarter of the index hospitalization. During months 13 through 24 following the index hospitalization, the excess direct medical cost was $ 5,941 ($23,215 in cases vs. $ 17,274 in controls, p<0.01).
conclusionsPneumonia occurs more frequently in elders with COPD than without COPD. The excess direct medical cost in elders with inpatient pneumonia extends up to 24 months following the index hospitalization and represents $28,638 in 2010 dollars.
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