Evidence map›Paper›PMID 24130524›Full record

ReviewFrontiers in human neuroscience2013

Cortical plasticity within and across lifetimes: how can development inform us about phenotypic transformations?

Leah Krubitzer, James C Dooley

Abstract readReview
In one paragraph

Review in Frontiers in human neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. "Natural Laboratory Complex" for novel primate neuroscience.Frontiers in integrative neuroscience · 2022
    Article
  6. Article
  7. Article
  8. Cognitive consequences of our grandmothering life history: cultural learning begins in infancy.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020
    Review
  9. Review
  10. Article
  11. Article
  12. The EMBO journal · 2018
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Leah KrubitzerCenter for Neuroscience, University of California Davis, Davis, CA, USA ; Department of Psychology, University of California Davis, Davis, CA, USA.
James C Dooley

Funding

Vision Science Training Program: Cornea to CortexT32EY015387 · NEI · UNIVERSITY OF CALIFORNIA DAVIS · PI MARIE E BURNS · 2003 to 2026
$4.8M
Can Cortical Plasticity be Directed and Amplified Following Early Loss of Vision?R01EY022987 · NEI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KRUBITZER, LEAH ANN · 2013 to 2016
$1.5M
NEI NIH HHS R01 EY022987NEI NIH HHS T32 EY015387
6 · The paper itself

Abstract

The neocortex is the part of the mammalian brain that is involved in perception, cognition, and volitional motor control. It is a highly dynamic structure that is dramatically altered within the lifetime of an animal and in different lineages throughout the course of evolution. These alterations account for the remarkable variations in behavior that species exhibit. Of particular interest is how these cortical phenotypes change within the lifetime of the individual and eventually evolve in species over time. Because we cannot study the evolution of the neocortex directly we use comparative analysis to appreciate the types of changes that have been made to the neocortex and the similarities that exist across taxa. Developmental studies inform us about how these phenotypic transitions may arise by alterations in developmental cascades or changes in the physical environment in which the brain develops. Both genes and the sensory environment contribute to aspects of the phenotype and similar features, such as the size of a cortical field, can be altered in a variety of ways. Although both genes and the laws of physics place constraints on the evolution of the neocortex, mammals have evolved a number of mechanisms that allow them to loosen these constraints and often alter the course of their own evolution.

Indexed as

comparative neuroanatomycortical developmentepigeneticEvo-Devoevolution

Identifiers

PMID24130524
PMCPMC3793242

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.