ReviewFrontiers in neural circuits2013
Dopamine signaling in reward-related behaviors.
Review in Frontiers in neural circuits, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 275 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
275 citing papers in PubMed, 5 syntheses or guidelines pooled it, 511 citations in OpenAlex.
- Dopaminergic Identity of SH-SY5Y Cells Across Differentiation Protocols in Parkinson's Disease Research: A Systematic Review.International journal of molecular sciences · 2026Pooled it
- Impact of digital addiction on youth health: A systematic review and meta-analysis.Journal of behavioral addictions · 2025Pooled it
- Glucagon-like peptide-1 receptor agonists for the treatment of opioid use disorders: a systematic review.Acta neuropsychiatrica · 2025Pooled it
- Assessing the Association Between Internet Addiction Disorder and Health Risk Behaviors Among Adolescents and Young Adults: A Systematic Review and Meta-Analysis.Frontiers in public health · 2022Pooled it
- The Role of Social Stress in the Development of Inhibitory Control Deficit: A Systematic Review in Preclinical Models.International journal of environmental research and public health · 2021Pooled it
- Alterations in reward network functional connectivity are associated with increased food addiction in obese individuals.Scientific reports · 2021Trial
- Pharmacogenetics of Dopamine β-Hydroxylase in cocaine dependence therapy with doxazosin.Addiction biology · 2019Trial
- Dual-target mu opioid-dopamine DEuropean journal of medicinal chemistry · 2026Article
- Structure-activity relationship of synthetic cathinones: integrated in silico, in vitro, and in vivo studies of α-PiHP analogues.Archives of toxicology · 2026Article
- Lactation increases food seeking and palatable feeding through mesolimbic dopamine signaling in mice.Cell reports · 2026Article
- Neuroligins and Neuropathic Pain: Insights into Synaptic Plasticity and Pain Transmission.Biology · 2026Review
- A genetically informed cross-lagged twin study of the longitudinal association between addiction-related behaviors and obesity.Addiction (Abingdon, England) · 2026Article
- Characterization of Neuronal Ensembles in a Model of Dual-Reward Conditioned Place Preference.eNeuro · 2026Article
- Superior colliculus modulates the compulsion in a model of addiction with foot-shock.Translational psychiatry · 2026Article
- FLP-15 functions through the GPCR NPR-3 to regulate local and global search behaviours in Caenorhabditis elegans.Communications biology · 2026Article
- Sex-dependent effects of short- and long-term social isolation on behavior and medial prefrontal DAT in rats.Scientific reports · 2026Article
- Disordered eating in adolescence: the roles of sensation seeking, weight status, and behavioral difficulties.Journal of eating disorders · 2026Article
- Mesolimbic dopamine signaling mediates increased hedonic feeding and food seeking in lactating mice.bioRxiv : the preprint server for biology · 2026Article
- Cocaine Use Disorder: Neuropathology and Exploratory Treatments.Molecular neurobiology · 2026Review
- The Regulatory Potential of Long Non-Coding RNAs in Bipolar Disorder.International journal of molecular sciences · 2026Review
215 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dopamine (DA) regulates emotional and motivational behavior through the mesolimbic dopaminergic pathway. Changes in DA mesolimbic neurotransmission have been found to modify behavioral responses to various environmental stimuli associated with reward behaviors. Psychostimulants, drugs of abuse, and natural reward such as food can cause substantial synaptic modifications to the mesolimbic DA system. Recent studies using optogenetics and DREADDs, together with neuron-specific or circuit-specific genetic manipulations have improved our understanding of DA signaling in the reward circuit, and provided a means to identify the neural substrates of complex behaviors such as drug addiction and eating disorders. This review focuses on the role of the DA system in drug addiction and food motivation, with an overview of the role of D1 and D2 receptors in the control of reward-associated behaviors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.