ArticleCanadian family physician Medecin de famille canadien2013
Integrated care for pregnant women on methadone maintenance treatment: Canadian primary care cohort study.
Article in Canadian family physician Medecin de famille canadien, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04251208 (MOms in REcovery), which is not on this map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
MOms in REcovery (MORE): Defining Optimal Care for Pregnant Women and Infants
Who cites it
16 citing papers in PubMed, 34 citations in OpenAlex.
- Polysubstance use in pregnancy: Findings from a population-based cross-sectional cohort study of pregnant women with opioid use.Drug and alcohol dependence · 2025Article
- Managing newborns at risk for neonatal abstinence syndrome (NAS)/neonatal opioid withdrawal syndrome (NOWS): Updates and emerging best practices.Paediatrics & child health · 2025Review
- La prise en charge des nouveau-nés à risque de syndrome d'abstinence néonatale et de syndrome de sevrage néonatal aux opioïdes : mises à jour et pratiques exemplaires émergentes.Paediatrics & child health · 2025Review
- Review
- Fostering Hope: Comprehensive Accessible Mother-Infant Dyad Care for Neonatal Abstinence (CAIN).Children (Basel, Switzerland) · 2022Article
- The Infant Cuddler Study: Evaluating the effectiveness of volunteer cuddling in infants with neonatal abstinence syndrome.Paediatrics & child health · 2020Article
- Research and policy priorities for addressing prenatal exposure to opioids in Alaska.International journal of circumpolar health · 2019Article
- Preventing vertical transmission of HCV in Canada.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2019Article
- "People in regular society don't think you can be a good mother and have a substance use problem": Participatory action research with women with substance use in pregnancy.Canadian family physician Medecin de famille canadien · 2018Article
- Managing infants born to mothers who have used opioids during pregnancy.Paediatrics & child health · 2018Article
- Psychiatric Co-Morbidities in Pregnant Women with Opioid Use Disorders: Prevalence, Impact, and Implications for Treatment.Current addiction reports · 2017Review
- Breastfeeding and Opiate Substitution Therapy: Starting to Understand Infant Feeding Choices.Substance abuse : research and treatment · 2016Review
- Review
- Maternal Substance Use and Neonatal Abstinence Syndrome: A Descriptive Study.Maternal and child health journal · 2015Article
- A glimpse of the future.Canadian family physician Medecin de famille canadien · 2013Article
- Optimizing Pregnancy Treatment Interventions for Moms (OPTI-Mom): A Pilot Study.Journal of addiction medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo describe the characteristics of a national cohort of pregnant women on methadone maintenance treatment (MMT) and to provide treatment outcome data for integrated care programs.
designRetrospective chart review.
settingThree different integrated care programs in geographically distinct cities: the Toronto Centre for Substance Use in Pregnancy in Toronto, Ont; the Herzl Family Practice Centre in Montreal, Que; and the Sheway clinic in Vancouver, BC.
participantsPregnant women meeting criteria for opioid dependence and attending an integrated care program between 1997 and 2009. Women were excluded if they were on MMT only for chronic pain.
main outcome measuresPatient demographic characteristics, concurrent medical and psychiatric disorders, and substance use outcome data.
resultsA total of 102 opioid-dependent pregnancies were included. The mean age was 29.7 years and 64% of women were white. Women in Montreal were more likely to have partners and had fewer children. Differences in living and housing situations among the sites tended to resolve by the time of delivery. Almost half of this cohort tested positive for hepatitis C. Women had a high prevalence of depression and anxiety across all sites. Half of this cohort was on MMT before conception and for the other half, MMT was initiated at a mean gestational age of 20.7 weeks, resulting in a mean dose of 82.4 mg at delivery. At the first visit, polysubstance use was common. Prescription opioid use was more frequent in Toronto and heroin use was more prevalent in Vancouver and Montreal. For the entire population, significant reductions were found by the time of delivery for illicit (P < .001) and prescription opioids (P = .001), cocaine (P < .001), marijuana (P = .009), and alcohol use (P < .001).
conclusionDespite geographic differences, all 3 integrated care programs have been associated with significant decreases in substance use in pregnant opioid-dependent women.
Indexed as
Identifiers
24130301PMC3796993W2165022883What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.