ArticleCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2013
Crystal methamphetamine and initiation of injection drug use among street-involved youth in a Canadian setting.
Article in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 3 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Health harms of non-medical prescription opioid use: A systematic review.Drug and alcohol review · 2022Pooled it
- Prevalence and Correlates of Providing and Receiving Assistance With the Transition to Injection Drug Use.Epidemiologic reviews · 2020Pooled it
- The experience of initiating injection drug use and its social context: a qualitative systematic review and thematic synthesis.Addiction (Abingdon, England) · 2017Pooled it
- Age, sex, and ethnic differences in substance use and/or substance use disorders among runaway and homeless youth: A meta-analysis and meta-regression.European child & adolescent psychiatry · 2026Review
- Latent polydrug use patterns and the provision of injection initiation assistance among people who inject drugs in three North American settings.Drug and alcohol review · 2023Article
- An answered call for aid? Cannabinoid clinical framework for the opioid epidemic.Harm reduction journal · 2023Review
- The influence of poly-drug use patterns on the association between opioid agonist treatment engagement and injecting initiation assistance.Substance abuse treatment, prevention, and policy · 2022Article
- Patterns of smoking and injecting methamphetamine and their association with health and social outcomes.Drug and alcohol review · 2021Article
- Frequent Cannabis Use Is Negatively Associated with Frequency of Injection Drug Use Among People Who Inject Drugs in a Canadian Setting.Cannabis and cannabinoid research · 2021Article
- Article
- Recent HIV testing and associated factors among people who use drugs in Cambodia: a national cross-sectional study.BMJ open · 2021Article
- Crystal methamphetamine use in British Columbia, Canada: A cross-sectional study of people who access harm reduction services.PloS one · 2021Article
- "Something that actually works": Cannabis use among young people in the context of street entrenchment.PloS one · 2020Article
- Initiation into heroin use among street-involved youth in a Canadian setting: A longitudinal cohort study.Drug and alcohol dependence · 2019Article
- Opioid agonist treatment scale-up and the initiation of injection drug use: A dynamic modeling analysis.PLoS medicine · 2019Article
- Residential eviction predicts initiation of or relapse into crystal methamphetamine use among people who inject drugs: a prospective cohort study.Journal of public health (Oxford, England) · 2019Article
- 3,4-Methylenedioxymethamphetamine (MDMA; ecstasy) use and transitions to injection drug use among street-involved youth.Substance abuse · 2019Article
- An age-based analysis of nonmedical prescription opioid use among people who use illegal drugs in Vancouver, Canada.Substance abuse treatment, prevention, and policy · 2018Article
- Article
- Cannabis use is associated with lower rates of initiation of injection drug use among street-involved youth: A longitudinal analysis.Drug and alcohol review · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundAlthough injection drug use is known to result in a range of health-related harms, including transmission of HIV and fatal overdose, little is known about the possible role of synthetic drugs in injection initiation. We sought to determine the effect of crystal methamphetamine use on risk of injection initiation among street-involved youth in a Canadian setting.
methodsWe used Cox regression analyses to identify predictors of injection initiation among injection-naive street-involved youth enrolled in the At-Risk Youth Study, a prospective cohort study of street-involved youth in Vancouver, British Columbia. Data on circumstances of first injection were also obtained.
resultsBetween October 2005 and November 2010, a total of 395 drug injection-naive, street-involved youth provided 1434 observations, with 64 (16.2%) participants initiating injection drug use during the follow-up period, for a cumulative incidence of 21.7 (95% confidence interval [CI] 1.7-41.7) per 100 person-years. In multivariable analysis, recent noninjection use of crystal methamphetamine was positively associated with subsequent injection initiation (adjusted hazard ratio 1.93, 95% CI 1.31-2.85). The drug of first injection was most commonly reported as crystal methamphetamine (14/31 [45%]).
interpretationNoninjection use of crystal methamphetamine predicted subsequent injection initiation, and crystal methamphetamine was the most commonly used drug at the time of first injection. Evidence-based strategies to prevent transition to injection drug use among crystal methamphetamine users are urgently needed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.