ArticleAngewandte Chemie (International ed. in English)2013
Water mediation is essential to nucleation of β-turn formation in peptide folding motifs.
Article in Angewandte Chemie (International ed. in English), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Probing Hydrogen-Bonding Preferences and Methyl Internal Rotation in Sotolon and Sotolon-(HInternational journal of molecular sciences · 2025Article
- Trimethylamine-N-oxide depletes urea in a peptide solvation shell.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Visualization of Self-Assembly and Hydration of a β-Hairpin through Integrated Small and Wide-Angle Neutron Scattering.Biomacromolecules · 2023Article
- Hydrogen Bonding and Solvation of a Proline-Based Peptide Model in Salt Solutions.Life (Basel, Switzerland) · 2021Article
- Hydrophobic-hydrophilic forces in protein folding.Biopolymers · 2017Article
- Studying the role of cooperative hydration in stabilizing folded protein states.Journal of structural biology · 2016Article
- Structure of the ordered hydration of amino acids in proteins: analysis of crystal structures.Acta crystallographica. Section D, Biological crystallography · 2015Article
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Authors and funding
5 authors.
Funding
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Abstract
Water-mediated bond formation: The structure of the peptide GPG-NH2 has been investigated in aqueous solution to understand the role of water in the formation of a β-turn. Using a combination of neutron diffraction enhanced by isotopic substitution, NMR spectroscopy, and computer simulations, it was found that water is an essential component to initiate folding in solution.
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