ArticleInfection2014
Surveillance of the first case of human avian influenza A (H7N9) virus in Beijing, China.
Article in Infection, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prognostic factors in H7N9 avian influenza: a systematic review based on case reports.BMC infectious diseases · 2026Pooled it
- Heterogeneous and Dynamic Prevalence of Asymptomatic Influenza Virus Infections.Emerging infectious diseases · 2016Pooled it
- Article
- A new reassortment of influenza A (H7N9) virus causing human infection in Beijing, 2014.Scientific reports · 2016Article
- A family cluster of three confirmed cases infected with avian influenza A (H7N9) virus in Zhejiang Province of China.BMC infectious diseases · 2014Article
- Circulation of reassortant influenza A(H7N9) viruses in poultry and humans, Guangdong Province, China, 2013.Emerging infectious diseases · 2014Article
- Continuing reassortment leads to the genetic diversity of influenza virus H7N9 in Guangdong, China.Journal of virology · 2014Article
- Effective strategy for managing H7N9 virus infection.Infection · 2014Article
- Effective strategy for managing H7N9 virus infection.Infection · 2014Article
Corrections and comments
- Commented on by
- Commented on by
Authors and funding
21 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeHuman infections with avian influenza A (H7N9) virus manifested in China in March 2013. The first case infected with H7N9 virus in Beijing involved a family member of a chicken dealer and was reported in April 2013. The clinical and epidemiological characteristics of this case and her parents were examined to illustrate some key traits regarding this novel H7N9 virus.
methodsThe index case was subjected to intensive clinical examination in order to observed the clinical process. Real-time PCR was used to confirm cases infected with H7N9 virus. The index case was administered oseltamivir (45 mg, twice daily) at the early stage of the infection. Sera were collected from the index case and her parents from the onset of illness onwards. The subjects were followed for 4 weeks.
resultsThe sera were confirmed by neutralizing antibody tests. The index case's clinical manifestation progressed quickly. The pharyngeal swab tested positive for influenza A based on the detection of influenza A antigen (rapid influenza diagnostic test) 15 h after the onset of fever and was positive for H7N9 virus. The patient's temperature dropped to 36.2 °C 18 h after treatment by oseltamivir (32 h after fever). Cough and other symptoms alleviated rapidly. A number of specimens from the environment of this cluster and from the feces specimens tested positive for viral RNA of the H7N9 virus on the fourth day following onset of the index case's illness. Pharyngeal swabs of the mother tested positive for H7N9 virus twice, but she showed no clinical symptoms. Four weeks after disease onset, the family did not present any clinical symptoms, and the results of the physical examination and blood tests were normal. The mother and the case's sera had a fourfold increased neutralizing antibody titer.
conclusionEarly diagnosis and early initiation of the treatment of confirmed infections is the most effective strategy for managing H7N9 virus infection. Human beings exposed to H7N9 virus may develop asymptomatic infection.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.