ArticlePediatric research2014
Modulation of EEG spectral edge frequency during patterned pneumatic oral stimulation in preterm infants.
Article in Pediatric research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.
What it found
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Who cites it
5 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Sensory-based interventions in the NICU: systematic review of effects on preterm brain development.Pediatric research · 2022Pooled it
- Non-nutritive sucking for increasing physiologic stability and nutrition in preterm infants.The Cochrane database of systematic reviews · 2016Pooled it
- Patterned frequency-modulated oral stimulation in preterm infants: A multicenter randomized controlled trial.PloS one · 2019Trial
- Frequency-modulated orocutaneous stimulation promotes non-nutritive suck development in preterm infants with respiratory distress syndrome or chronic lung disease.Journal of perinatology : official journal of the California Perinatal Association · 2014Trial
- Structural and functional brain asymmetries in the early phases of life: a scoping review.Brain structure & function · 2022Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundStimulation of the nervous system plays a central role in brain development and neurodevelopmental outcomes. Thalamocortical and corticocortical development is diminished in premature infants and correlated to electroencephalography (EEG) progression. The purpose of this study was to determine the effects of orocutaneous stimulation on the modulation of spectral edge frequency fc = 90% (SEF-90), which is derived from EEG recordings in preterm infants.
methodsA total of 22 preterm infants were randomized to experimental and control conditions. Pulsed orocutaneous stimulation was presented during gavage feedings begun at ~32 wk postmenstrual age. The SEF-90 was derived from two-channel EEG recordings.
resultsCompared with the control condition, the pulsed orocutaneous stimulation produced a significant reorganization of SEF-90 in the left (P = 0.005) and right (P < 0.0001) hemispheres. Notably, the left and right hemispheres showed a reversal in the polarity of frequency shift, demonstrating hemispheric asymmetry in the frequency domain. Pulsed orocutaneous stimulation also produced a significant pattern of short-term cortical adaptation and a long-term neural adaptation manifested as a 0.5 Hz elevation in SEF-90 after repeated stimulation sessions.
conclusionThis is the first study to demonstrate the modulating effects of a servo-controlled oral somatosensory input on the spectral features of EEG activity in preterm infants.
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