ReviewNutrients2013
Anorexia of aging: a modifiable risk factor for frailty.
Review in Nutrients, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed, 2 syntheses or guidelines pooled it, 148 citations in OpenAlex.
- Applying the Bradford Hill Criteria to Assess the Independent Causal Roles of Aging and Medication in Frailty Progression: A Systematic Review.Drugs & aging · 2026Pooled it
- Pooled it
- Prevalence of food allergies in older adults: A systematic review and meta-analysis.The World Allergy Organization journal · 2026Review
- Are GLP-1 receptor agonists gerotherapeutics or just treatments for obesity?Nature aging · 2026Article
- Identification of pre-frail/frail older adults using the Integrated Care for Older People WHO Step1 screening tool: a cross sectional study.International journal of nursing studies advances · 2026Article
- Article
- Effect of taste recall training using 5 sweet substances on sweet taste sensitivities.Chemical senses · 2025Article
- Comparative effects of oral nutritional supplementation vs. nutritional education on appetite and weight in older adults with anorexia of aging: a 12-week non-randomized controlled trial.Frontiers in nutrition · 2025Article
- Article
- Food allergies in older people: An emerging health problem.The World Allergy Organization journal · 2024Review
- The role of zinc on nutritional status, sarcopenia, and frailty in older adults: a scoping review.Nutrition reviews · 2024Article
- The associations between sleep quality, mood, pain and appetite in community dwelling older adults: a daily experience study.The journal of nutrition, health & aging · 2024Article
- Exploring the experience of appetite loss in older age: insights from a qualitative study.BMC geriatrics · 2024Article
- Review
- A Novel Frailty Score Based on Laboratory Parameters (FIMS Score) for the Management of Older Patients with Severe Aortic Stenosis.Journal of clinical medicine · 2023Article
- Validation of a telephone-based administration of the simplified nutritional appetite questionnaire.Journal of cachexia, sarcopenia and muscle · 2023Article
- Two-year longitudinal associations between nutritional status and frailty in community-dwelling older adults: Korean Frailty and Aging Cohort Study.BMC geriatrics · 2023Article
- Effects ofAntioxidants (Basel, Switzerland) · 2023Article
- Handgrip strength and risk of malnutrition are associated with an increased risk of hospitalizations in inflammatory bowel disease patients.Therapeutic advances in gastroenterology · 2023Article
- Untangling the Complex Interplay between Social Isolation, Anorexia, Sarcopenia, and Mortality: Insights from a Longitudinal Study.The journal of nutrition, health & aging · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anorexia of aging, defined as a loss of appetite and/or reduced food intake, affects a significant number of elderly people and is far more prevalent among frail individuals. Anorexia recognizes a multifactorial origin characterized by various combinations of medical, environmental and social factors. Given the interconnection between weight loss, sarcopenia and frailty, anorexia is a powerful, independent predictor of poor quality of life, morbidity and mortality in older persons. One of the most important goals in the management of older, frail people is to optimize their nutritional status. To achieve this objective it is important to identify subjects at risk of anorexia and to provide multi-stimulus interventions that ensure an adequate amount of food to limit and/or reverse weight loss and functional decline. Here, we provide a brief overview on the relevance of anorexia in the context of sarcopenia and frailty. Major pathways supposedly involved in the pathogenesis of anorexia are also illustrated. Finally, the importance of treating anorexia to achieve health benefits in frail elders is highlighted.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.