Evidence map›Paper›PMID 24128740›Full record

SynthesisNeuroImage2014

Selection and stopping in voluntary action: a meta-analysis and combined fMRI study.

Charlotte L Rae, Laura E Hughes, Chelan Weaver, Michael C Anderson, James B Rowe

Abstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in NeuroImage, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Article
  13. Review
  14. Article
  15. Article
  16. Cortical and white matter substrates supporting visuospatial working memory.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2024
    Article
  17. Review
  18. Article
  19. Article
  20. Article

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Charlotte L RaeMRC Cognition and Brain Sciences Unit, Cambridge CB2 7EF, UK. Electronic address: charlotte.rae@mrc-cbu.cam.ac.uk.
Laura E HughesMRC Cognition and Brain Sciences Unit, Cambridge CB2 7EF, UK; Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 2QQ, UK.
Chelan WeaverMRC Cognition and Brain Sciences Unit, Cambridge CB2 7EF, UK.
Michael C AndersonMRC Cognition and Brain Sciences Unit, Cambridge CB2 7EF, UK; Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge CB2 3EB, UK.
James B RoweMRC Cognition and Brain Sciences Unit, Cambridge CB2 7EF, UK; Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 2QQ, UK; Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge CB2 3EB, UK.

Funding

Medical Research Council G0001354Medical Research Council G1000183Medical Research Council MC_U105597119Medical Research Council MC_U105597121Wellcome Trust 088324
6 · The paper itself

Abstract

Voluntary action control requires selection of appropriate responses and stopping of inappropriate responses. Selection and stopping are often investigated separately, but they appear to recruit similar brain regions, including the pre-supplementary motor area (preSMA) and inferior frontal gyrus. We therefore examined the evidence for overlap of selection and stopping using two approaches: a meta-analysis of existing studies of selection and stopping, and a novel within-subject fMRI study in which action selection and a stop signal task were combined factorially. The novel fMRI study also permitted us to investigate hypotheses regarding a common mechanism for selection and stopping. The preSMA was identified by both methods as common to selection and stopping. However, stopping a selected action did not recruit preSMA more than stopping a specified action, nor did stop signal reaction times differ significantly across the two conditions. These findings suggest that the preSMA supports both action selection and stopping, but the two processes may not require access to a common inhibition mechanism. Instead, the preSMA might represent information about potential actions that is used in both action selection and stopping in order to resolve conflict between competing available responses.

Indexed as

Inhibition, PsychologicalBrainBrain MappingDecision MakingHumansMagnetic Resonance ImagingVolitionAction selectionAction stoppingfalse discovery rate cluster correctedFDRcfMRIfunctional magnetic resonance imagingInferior frontal gyrusInhibitionpreSMApre-supplementary motor areaPre-supplementary motor areareaction timeRTSSRTstop signal reaction timeStop signal task

Identifiers

PMID24128740
PMCPMC3898966

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.