Trial reportDrug and alcohol dependence2014
Integration of health services improves multiple healthcare outcomes among HIV-infected people who inject drugs in Ukraine.
Trial report in Drug and alcohol dependence, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
61 citing papers in PubMed, 4 syntheses or guidelines pooled it, 88 citations in OpenAlex.
- Methods to derive composite indicators used for quality and safety measurement and monitoring in healthcare: a scoping review.Frontiers in health services · 2026Pooled it
- Is co-location of services with HIV care associated with improved HIV care outcomes? A systematic review.AIDS care · 2019Pooled it
- Integration of care for HIV and opioid use disorder.AIDS (London, England) · 2019Pooled it
- Integrating HIV and substance use services: a systematic review.Journal of the International AIDS Society · 2017Pooled it
- Design and implementation of a Type-2 hybrid, prospective randomized trial of opioid agonist therapies integration into primary care clinics in Ukraine.Contemporary clinical trials · 2024Trial
- Integrated care van delivery of evidence-based services for people who inject drugs: A cluster-randomized trial.Addiction (Abingdon, England) · 2024Trial
- Expanding single-venue services to better engage young people who inject drugs: insights from India.Harm reduction journal · 2024Review
- Prevalence and Correlates of Depression and Bipolar Disorder Among Patients Maintained on Methadone and Buprenorphine in Ukraine.International journal of mental health and addiction · 2024Article
- Experience delivering an integrated service model to people with criminal justice system involvement and housing insecurity.BMC public health · 2023Article
- The development and initial validation of the Russian version of the BASIS-24.Addiction science & clinical practice · 2022Review
- Methadone within prison and linkage to and retention in treatment upon community release for people with opioid use disorder in Kyrgyzstan: Evaluation of a national program.The International journal on drug policy · 2022Article
- Preliminary analysis of self-reported quality health indicators of patients on opioid agonist therapy at specialty and primary care clinics in Ukraine: A randomized control trial.PLOS global public health · 2022Article
- Barriers and facilitators of HIV and hepatitis C care among people who inject drugs in Nairobi, Kenya: a qualitative study with peer educators.Harm reduction journal · 2021Article
- Article
- Serving the Co-Morbid Mental Health and Substance Use Needs of People with HIV.Community mental health journal · 2021Article
- "You need money to get high, and that's the easiest and fastest way:" A typology of sex work and health behaviours among people who inject drugs.The International journal on drug policy · 2021Article
- Healthcare delivery for HIV-positive people with tuberculosis in Europe.HIV medicine · 2021Article
- The real-world impact of dosing of methadone and buprenorphine in retention on opioid agonist therapies in Ukraine.Addiction (Abingdon, England) · 2021Observational
- Collaborative tuberculosis/HIV activities in the European Region.ERJ open research · 2021Article
- "Health Is on the Back Burner:" Multilevel Barriers and Facilitators to Primary Care Among People Who Inject Drugs.Journal of general internal medicine · 2021Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundPeople who inject drugs (PWID) experience poor outcomes and fuel HIV epidemics in middle-income countries in Eastern Europe and Central Asia. We assess integrated/co-located (ICL) healthcare for HIV-infected PWID, which despite international recommendations, is neither widely available nor empirically examined.
methodsA 2010 cross-sectional study randomly sampled 296 HIV-infected opioid-dependent PWID from two representative HIV-endemic regions in Ukraine where ICL, non-co-located (NCL) and harm reduction/outreach (HRO) settings are available. ICL settings provide onsite HIV, addiction, and tuberculosis services, NCLs only treat addiction, and HROs provide counseling, needles/syringes, and referrals, but no opioid substitution therapy (OST). The primary outcome was receipt of quality healthcare, measured using a quality healthcare indicator (QHI) composite score representing percentage of eight guidelines-based recommended indicators met for HIV, addiction and tuberculosis treatment. The secondary outcomes were individual QHIs and health-related quality-of-life (HRQoL).
resultsOn average, ICL-participants had significantly higher QHI composite scores compared to NCL- and HRO-participants (71.9% versus 54.8% versus 37.0%, p<0.001) even after controlling for potential confounders. Compared to NCL-participants, ICL-participants were significantly more likely to receive antiretroviral therapy (49.5% versus 19.2%, p<0.001), especially if CD4 ≤ 200 (93.8% versus 62.5% p<0.05); guideline-recommended OST dosage (57.3% versus 41.4%, p<0.05); and isoniazid preventive therapy (42.3% versus 11.2%, p<0.001). Subjects receiving OST had significantly higher HRQoL than those not receiving it (p<0.001); however, HRQoL did not differ significantly between ICL- and NCL-participants.
conclusionsThese findings suggest that OST alone improves quality-of-life, while receiving care in integrated settings collectively and individually improves healthcare quality indicators for PWID.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.