Evidence map›Paper›PMID 24128013›Full record

ArticleBMC microbiology2013

Molecular analysis of subtilase cytotoxin genes of food-borne Shiga toxin-producing Escherichia coli reveals a new allelic subAB variant.

Joschua Funk, Helen Stoeber, Elisabeth Hauser, Herbert Schmidt

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in BMC microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. EnterohemorrhagicInternational journal of molecular sciences · 2022
    Review
  3. Review
  4. Article
  5. Article
  6. Variants ofToxins · 2019
    Article
  7. Transcription of the Subtilase Cytotoxin GeneApplied and environmental microbiology · 2019
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Characteristics of Shigatoxin-ProducingFrontiers in microbiology · 2017
    Article
  13. Article
  14. Toxic phytochemicals and their potential risks for human cancer.Cancer prevention research (Philadelphia, Pa.) · 2015
    Review
4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Joschua Funk
Helen Stoeber
Elisabeth Hauser
Herbert SchmidtDepartment of Food Microbiology, Institute of Food Science and Biotechnology, University of Hohenheim, Garbenstraße 28, Stuttgart, D-70599, Germany. herbert.schmidt@uni-hohenheim.de.
University of Hohenheim · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe open reading frames of subAB genes and their flanking regions of 18 food-borne Shiga toxin-producing E. coli (STEC) strains were analyzed.

resultsAll but one subAB open reading frames (ORF) were complete in all STEC strains. The subAB1 genes of nine STEC strains were located on large plasmids. The subAB2 allele (here designated subAB2-1), which was recently described by others to be present in the Subtilase-Encoding PAI (SE-PAI) was found in 6 STEC strains. A new chromosomal subAB2 variant, designated subAB2-2 was detected in 6 strains and was linked to a chromosomal gene hypothetically encoding an outer membrane efflux protein (OEP). Three STEC strains contained both subAB2 variants. DNA analysis indicated sequence conservation in the plasmid-located alleles and sequence heterogeneity among the chromosomal subAB2 genes.

conclusionsThe results of this study have shown that 18 subAB-PCR positive STEC strains contain complete subAB open reading frames. Furthermore, the new allelic variant subAB2-2 was described, which can occur in addition to subAB2-1 on a new chromosomal locus.

Indexed as

Food MicrobiologyGenetic VariationAllelesChromosomes, BacterialDNA, BacterialEscherichia coli ProteinsGenetic LociHumansMolecular Sequence DataOpen Reading FramesPlasmidsSequence Analysis, DNAShiga-Toxigenic Escherichia coliSubtilisinsDNA, BacterialEscherichia coli Proteinssubtilase cytotoxin, E coliSubtilisins

Identifiers

PMID24128013
PMCPMC3852854
OpenAlexW2017756638

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.