ReviewInternational reviews of immunology
Immunosenescence and immune response in organ transplantation.
Review in International reviews of immunology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed.
- Immunosenescence in Human Disease: Mechanistic Insights and Therapeutic Opportunities.Biomolecules & therapeutics · 2026Review
- Necessity of induction agent modification for old age kidney transplant recipients.Kidney research and clinical practice · 2025Article
- Age and liver transplantation: a key factor in clinical outcomes? single center study in Argentina.Frontiers in aging · 2025Article
- Impact of Immunosenescence in Older Kidney Transplant Recipients: Associated Clinical Outcomes and Possible Risk Stratification for Immunosuppression Reduction.Drugs & aging · 2024Review
- Current and emerging tools for simultaneous assessment of infection and rejection risk in transplantation.Frontiers in immunology · 2024Review
- Clinical perspectives on the age-related increase of immunosuppressive activity.Journal of molecular medicine (Berlin, Germany) · 2022Review
- Investigating population-level immunosenescence: From bench to bedside.Frontiers in immunology · 2022Review
- The Risk of Postkidney Transplant Outcomes by Induction Choice Differs by Recipient Age.Transplantation direct · 2021Article
- Immunosuppression Considerations for Older Kidney Transplant Recipients.Current transplantation reports · 2021Article
- An evaluation of the recognised systemic inflammatory biomarkers of chronic sub-optimal inflammation provides evidence for inflammageing (IFA) during multiple sclerosis (MS).Immunity & ageing : I & A · 2021Review
- CTLA4-Ig prolongs graft survival specifically in young but not old mice.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021Article
- Transplant of Elderly Patients: Is There an Upper Age Cutoff?Clinics in liver disease · 2021Review
- DNA Methylation Age Is More Closely Associated With Infection Risk Than Chronological Age in Kidney Transplant Recipients.Transplantation direct · 2020Article
- Remodeling of the Immune Response With Aging: Immunosenescence and Its Potential Impact on COVID-19 Immune Response.Frontiers in immunology · 2020Review
- Changes of T-cell Immunity Over a Lifetime.Transplantation · 2019Review
- Differences in Gene Expression in Older Compared With Younger Kidney Transplant Recipients.Transplantation direct · 2019Article
- Increased T cell immunosenescence and accelerated maturation phenotypes in older kidney transplant recipients.Human immunology · 2018Article
- Association of Cold Ischemia Time With Acute Renal Transplant Rejection.Transplantation · 2018Article
- The Autoimmune-Associated Single Nucleotide Polymorphism WithinFrontiers in immunology · 2018Article
- Differences in Phenotypes and Liver Transplantation Outcomes by Age Group in Patients with Primary Sclerosing Cholangitis.Digestive diseases and sciences · 2017Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
The immune system undergoes a complex and continuous remodeling with aging. Immunosenescence results into both quantitative and qualitative changes of specific cellular subpopulations that have major impact on allorecognition and alloresponse, and consequently on graft rejection and tolerance. Here, we are going to review the immunological changes associated with the aging process relevant for transplantation. Interventions to selectively target changes associated with the senescence process seem promising therapeutic strategies to improve transplantation outcome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.