Evidence map›Paper›PMID 24127622›Full record

Trial reportPsychosomatic medicine2013

Randomized controlled trial of mindfulness-based stress reduction for prehypertension.

Joel W Hughes, David M Fresco, Rodney Myerscough, Manfred H M van Dulmen, Linda E Carlson, Richard Josephson

3 registry-linked trialsOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Psychosomatic medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 59 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 9 pooled it
14.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00440596 nacompletednot on this map

Mindfulness Based Stress Reduction for High Blood Pressure

TypeinterventionalSponsorKent State UniversityRan2006 to 2009Enrolled56ConditionsHypertensionArmsMindfulness based stress reduction, Progressive Muscle Relaxation
NCT02371317 naunknown statusnot on this mapstarted 2015, after this paper: background citation

Stress Management for High Blood Pressure

TypeinterventionalSponsorKent State UniversityRan2015 to 2020Enrolled141ConditionsPrehypertensionArmsMindfulness-Based Stress Reduction, Stress Management Education, American Heart Association Recommended Self-Care
NCT02830529 nacompletednot on this mapstarted 2015, after this paper: background citation

Mindfulness Attitude to Deliver Dietary Approach to Stop Hypertension

TypeinterventionalSponsorCase Western Reserve UniversityRan2015 to 2017Enrolled31ConditionsPrehypertensionArmsMAD DASH, DASH diet education
3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 9 syntheses or guidelines pooled it, 143 citations in OpenAlex.

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  12. Quality of life in adults with autism spectrum disorder: influence of age, sex, and a controlled, randomized mindfulness-based stress reduction pilot intervention.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
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  18. Mindfulness meditation alleviates fibromyalgia symptoms in women: results of a randomized clinical trial.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2015
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Joel W HughesDepartment of Psychology, PO Box 5190, Kent, OH 44242. jhughes1@kent.edu.
David M Fresco
Rodney Myerscough
Manfred H M van Dulmen
Linda E Carlson
Richard Josephson
Summa Health System · USCommittee on Publication Ethics · GBKent State University · USUniversity of Calgary · CA

Funding

Mindfulness-based Stress Reduction For High Blood PressureR21AT002698 · NCCIH · KENT STATE UNIVERSITY · PI HUGHES, JOEL W · 2006 to 2007
$537k
NCCIH NIH HHS 1R21AT002698-01A2NCCIH NIH HHS R21 AT002698
6 · The paper itself

Abstract

objectiveMindfulness-based stress reduction (MBSR) is an increasingly popular practice demonstrated to alleviate stress and treat certain health conditions. MBSR may reduce elevated blood pressure (BP). Treatment guidelines recommend life-style modifications for BP in the prehypertensive range (systolic BP [SBP] 120-139 mm Hg or diastolic BP [DBP] 80-89 mm Hg), followed by antihypertensives if BP reaches hypertensive levels. MBSR has not been thoroughly evaluated as a treatment of prehypertension. A randomized clinical trial of MBSR for high BP was conducted to determine whether BP reductions associated with MBSR exceed those observed for an active control condition consisting of progressive muscle relaxation (PMR) training.

methodsFifty-six men (43%) and women (57%) averaging (standard deviation) 50.3 (6.5) years of age (91% white) with unmedicated BP in the prehypertensive range were randomized to 8 weeks of MBSR or PMR delivered in a group format. Treatment sessions were administered by one treatment provider and lasted approximately 2.5 hours each week. Clinic BP was the primary outcome measure. Ambulatory BP was a secondary outcome measure.

resultsAnalyses were based on intent to treat. Patients randomized to MBSR exhibited a 4.8-mm Hg reduction in clinic SBP, which was larger than the 0.7-mm Hg reduction observed for PMR (p = .016). Those randomized to MBSR exhibited a 1.9-mm Hg reduction in DBP compared with a 1.2-mm Hg increase for PMR (p = .008). MBSR did not result in larger decreases in ambulatory BP than in PMR.

conclusionsMBSR resulted in a reduction in clinic SBP and DBP compared with PMR. Trial Registration ClinicalTrials.gov identifier: NCT00440596.

Indexed as

AdultAnalysis of VarianceBlood PressureBlood Pressure Monitoring, AmbulatoryFemaleHumansIntention to Treat AnalysisLinear ModelsMaleMiddle AgedMindfulnessOutcome Assessment, Health CarePatient DropoutsPractice Guidelines as TopicPrehypertensionRelaxation Therapyblood pressureclinical trialMBSRmeditationmindfulnessprehypertension

Identifiers

PMID24127622
PMCPMC3834730
OpenAlexW1991191692

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.