Evidence map›Paper›PMID 24127340›Full record

ArticleProtein science : a publication of the Protein Society2013

The dataset for protein-RNA binding affinity.

Xiufeng Yang, Haotian Li, Yangyu Huang, Shiyong Liu

Abstract read
In one paragraph

Article in Protein science : a publication of the Protein Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
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  3. Targeting RNA adenosine editing and modification enzymes for RNA therapeutics.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
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  13. Understanding mMolecular biotechnology · 2019
    Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Reading mTrends in cell biology · 2018
    Review
  20. The yeast transcription elongation factor Spt4/5 is a sequence-specific RNA binding protein.Protein science : a publication of the Protein Society · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiufeng YangBiomolecular Physics and Modeling Group, Department of Physics, Huazhong University of Science and Technology, Wuhan, 430074, Hubei, China.
Haotian Li
Yangyu Huang
Shiyong Liu

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have developed a non-redundant protein-RNA binding benchmark dataset derived from the available protein-RNA structures in the Protein Database Bank. It consists of 73 complexes with measured binding affinity. The experimental conditions (pH and temperature) for binding affinity measurements are also listed in our dataset. This binding affinity dataset can be used to compare and develop protein-RNA scoring functions. The predicted binding free energy of the 73 complexes from three available scoring functions for protein-RNA docking has a low correlation with the binding Gibbs free energy calculated from Kd.

Indexed as

Data CollectionComputational BiologyComputer SimulationCrystallography, X-RayDatabases, ProteinMolecular Docking SimulationProtein BindingProteinsProteomicsRNARNA-Binding ProteinsThermodynamicsProteinsRNARNA-Binding Proteinsbinding affinity benchmarkbinding free energyprotein-RNA dockingscoring function

Identifiers

PMID24127340
PMCPMC3843634

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.