Evidence map›Paper›PMID 24127293›Full record

ArticleAdvanced materials (Deerfield Beach, Fla.)2014

Biophysically defined and cytocompatible covalently adaptable networks as viscoelastic 3D cell culture systems.

Daniel D McKinnon, Dylan W Domaille, Jennifer N Cha, Kristi S Anseth

Abstract readValidation Study
In one paragraph

Article in Advanced materials (Deerfield Beach, Fla.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 183 papers.

0numbers the graph read from it
0cells of the map it votes in
183citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

183 citing papers in PubMed.

  1. Article
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  13. Next-Generation Hydrogels for Biliary Organoid Engineering.Pharmaceuticals (Basel, Switzerland) · 2025
    Review
  14. Review
  15. Article
  16. Article
  17. Review
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  19. Article
  20. Article

123 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Daniel D McKinnonDepartment of Chemical and Biological Engineering, University of Colorado Boulder, Jennie Smoly Caruthers Biotechnology Building, 3415 Colorado Ave, 596 UCB, Boulder, CO, 80303; BioFrontiers Institute, University of Colorado Boulder, Jennie Smoly Caruthers Biotechnology Building, 3415 Colorado Ave, 596 UCB, Boulder, CO, 80303.
Dylan W Domaille
Jennifer N Cha
Kristi S Anseth

Funding

LEADERSHIP TRAINING IN PHARMACEUTICAL BIOTECHNOLOGYT32GM008732 · NIGMS · UNIVERSITY OF COLORADO AT BOULDER · PI RANDOLPH, THEODORE W · 2001 to 2015
$2.7M
Howard Hughes Medical InstituteNIGMS NIH HHS 5 T32 GM 8732NIGMS NIH HHS T32 GM008732
6 · The paper itself

Abstract

Presented here is a cytocompatible covalently adaptable hydrogel uniquely capable of mimicking the complex biophysical properties of native tissue and enabling natural cell functions without matrix degradation. Demonstrated is both the ability to control elastic modulus and stress relaxation time constants by more than an order of magnitude while predicting these values based on fundamental theoretical understanding and the simulation of muscle tissue and the encapsulation of myoblasts.

Indexed as

Cell Culture TechniquesAldehydesAnimalsBenzaldehydesBiocompatible MaterialsBiophysical PhenomenaCell LineCell SurvivalElastic ModulusHydrazonesHydrogelsKineticsMiceMuscle CellsMuscle, SkeletalMyoblasts4-nitrobenzaldehydeAldehydesbenzaldehydeBenzaldehydesBiocompatible MaterialsbutyraldehydeHydrazonesHydrogelsPolyethylene GlycolsViscoelastic Substancesdynamic materialshydrogelspolymeric materialsself-healing materialssupramolecular chemistry

Identifiers

PMID24127293
PMCPMC4582033

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.