Evidence map›Paper›PMID 24127165›Full record

ReviewJournal of autism and developmental disorders2015

Use of transcranial magnetic stimulation in autism spectrum disorders.

Lindsay M Oberman, Alexander Rotenberg, Alvaro Pascual-Leone

4 registry-linked trialsOpen access · greenAbstract readReview
In one paragraph

Review in Journal of autism and developmental disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04242355 naactive not recruitingnot on this mapstarted 2019, after this paper: background citation

Effects of Repetitive Transcranial Magnetic Stimulation on Neural and Behavioral Facets of Social Cognition in Autism Spectrum Disorder

TypeinterventionalSponsorYale UniversityRan2019 to 2027Enrolled100ConditionsAutism Spectrum DisorderArmsTranscranial Magnetic Stimulation (TMS)
NCT04532424 narecruitingnot on this mapstarted 2021, after this paper: background citation

Transcranial Magnetic Stimulation for Restricted and Repetitive Behavior in ASD

TypeinterventionalSponsorStanford UniversityRan2021 to 2029Enrolled67ConditionsAutism Spectrum Disorder, Autism, Asperger SyndromeArmsTranscranial magnetic stimulation
NCT04936009 narecruitingnot on this mapstarted 2022, after this paper: background citation

Noninvasive Brain Stimulation to Treat Core Social Deficits in Autism Spectrum Disorder

TypeinterventionalSponsorYale UniversityRan2022 to 2027Enrolled60ConditionsAutism Spectrum DisorderArmsTranscranial Magnetic Stimulation (TMS)
NCT06524310 nacompletednot on this mapstarted 2024, after this paper: background citation

Effects of Repetitive Transcranial Magnetic Stimulation (rTMS) on Cognitive Functions and Behavior in Individuals With Autism Spectrum Disorder ( ASD)

TypeinterventionalSponsorKing Saud UniversityRan2024 to 2025Enrolled35ConditionsAutism Spectrum DisorderArmsStimulation with low frequency rTMS at 1 Hz
3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 101 citations in OpenAlex.

  1. Pooled it
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  15. Non-invasive stimulation of the social brain: the methodological challenges.Social cognitive and affective neuroscience · 2022
    Review
  16. Article
  17. Article
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  19. Treatment of Adults with Autism and Major Depressive Disorder Using Transcranial Magnetic Stimulation: An Open Label Pilot Study.Autism research : official journal of the International Society for Autism Research · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Lindsay M ObermanBerenson-Allen Center for Noninvasive Brain Stimulation, and Division of Cognitive Neurology, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, KS 158, Boston, MA, 02215, USA.
Alexander Rotenberg
Alvaro Pascual-Leone
Beth Israel Deaconess Medical Center · US

Funding

Harvard Clinical and Translational Science Center (KL2)KL2RR025757 · NCRR · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2008 to 2011
$4.1M
Cortical Plasticity in Autism Spectrum DisordersR01MH100186 · NIMH · BETH ISRAEL DEACONESS MEDICAL CENTER · PI ROTENBERG, ALEXANDER · 2014 to 2018
$2.2M
NCRR NIH HHS KL2 RR025757NIMH NIH HHS R01 MH100186
6 · The paper itself

Abstract

The clinical, social and financial burden of autism spectrum disorder (ASD) is staggering. We urgently need valid and reliable biomarkers for diagnosis and effective treatments targeting the often debilitating symptoms. Transcranial magnetic stimulation (TMS) is beginning to be used by a number of centers worldwide and may represent a novel technique with both diagnostic and therapeutic potential. Here we critically review the current scientific evidence for the use of TMS in ASD. Though preliminary data suggests promise, there is simply not enough evidence yet to conclusively support the clinical widespread use of TMS in ASD, neither diagnostically nor therapeutically. Carefully designed and properly controlled clinical trials are warranted to evaluate the true potential of TMS in ASD.

Indexed as

Child Development Disorders, PervasiveHumansTranscranial Magnetic StimulationTreatment Outcome

Identifiers

PMID24127165
PMCPMC4519010
OpenAlexW2016884615

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.