ArticleEuropean radiology2014
Radiation dose reduction in cerebral CT perfusion imaging using iterative reconstruction.
Article in European radiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Letter to the Editor: Cerebral CT perfusion dose: diagnostic reference levels should stimulate, not replace, optimization.Insights into imaging · 2026Article
- Comparison of preoperative and postoperative ct foot perfusion in patients undergoing infrapopliteal bypass for peripheral arterial disease.BMC cardiovascular disorders · 2026Article
- Effectiveness of low-tube current for reducing radiation dose in cerebral computed tomography perfusion.Archives of medical science : AMS · 2026Article
- Optimizing Radiation Dose and Image Quality in Stroke CT Protocols: Proposed Diagnostic Reference Levels for Multiphase CT Angiography and Perfusion Imaging.Diagnostics (Basel, Switzerland) · 2024Article
- The value of a deep learning image reconstruction algorithm in whole-brain computed tomography perfusion in patients with acute ischemic stroke.Quantitative imaging in medicine and surgery · 2023Article
- Reduction in Radiation Exposure of CT Perfusion by Optimized Imaging Timing Using Temporal Information of the Preceding CT Angiography of the Carotid Artery in the Stroke Protocol.Diagnostics (Basel, Switzerland) · 2022Article
- Iterative reconstruction algorithm improves the image quality without affecting quantitative measurements of computed tomography perfusion in the upper abdomen.European journal of radiology open · 2020Article
- Statistical properties of cerebral CT perfusion imaging systems. Part I. Cerebral blood volume maps generated from nondeconvolution-based systems.Medical physics · 2019Article
- Effect of prolonged acquisition intervals for CT-perfusion analysis methods in patients with ischemic stroke.Medical physics · 2019Article
- Low-dose CT perfusion with projection view sharing.Medical physics · 2018Article
- Low-Dose Volume-Perfusion CT of the Brain: Effects of Radiation Dose Reduction on Performance of Perfusion CT Algorithms.Clinical neuroradiology · 2017Article
- Adaptive statistical iterative reconstruction improves image quality without affecting perfusion CT quantitation in primary colorectal cancer.European journal of radiology open · 2017Article
- 128-slice CT angiography of the aorta without ECG-gating: efficacy of faster gantry rotation time and iterative reconstruction in terms of image quality and radiation dose.European radiology · 2016Article
- Impact of image denoising on image quality, quantitative parameters and sensitivity of ultra-low-dose volume perfusion CT imaging.European radiology · 2016Article
- Iterative Reconstruction Improves Both Objective and Subjective Image Quality in Acute Stroke CTP.PloS one · 2016Article
- Reduced-dose CT protocol for the assessment of cerebral vasospasm.Neuroradiology · 2015Article
- Effects of radiation dose reduction in Volume Perfusion CT imaging of acute ischemic stroke.European radiology · 2015Article
- Improvement of image quality and radiation dose of CT perfusion of the brain by means of low-tube voltage (70 KV).European radiology · 2014Article
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9 authors.
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Abstract
objectivesTo investigate whether iterative reconstruction (IR) in cerebral CT perfusion (CTP) allows for 50% dose reduction while maintaining image quality (IQ).
methodsA total of 48 CTP examinations were reconstructed into a standard dose (150 mAs) with filtered back projection (FBP) and half-dose (75 mAs) with two strengths of IR (middle and high). Objective IQ (quantitative perfusion values, contrast-to-noise ratio (CNR), penumbra, infarct area and penumbra/infarct (P/I) index) and subjective IQ (diagnostic IQ on a four-point Likert scale and overall IQ binomial) were compared among the reconstructions.
resultsHalf-dose CTP with high IR level had, compared with standard dose with FBP, similar objective (grey matter cerebral blood volume (CBV) 4.4 versus 4.3 mL/100 g, CNR 1.59 versus 1.64 and P/I index 0.74 versus 0.73, respectively) and subjective diagnostic IQ (mean Likert scale 1.42 versus 1.49, respectively). The overall IQ in half-dose with high IR level was scored lower in 26-31%. Half-dose with FBP and with the middle IR level were inferior to standard dose with FBP.
conclusionWith the use of IR in CTP imaging it is possible to examine patients with a half dose without significantly altering the objective and diagnostic IQ. The standard dose with FBP is still preferable in terms of subjective overall IQ in about one quarter of patients. KEY POINTS: • Computed tomography perfusion (CTP) is increasingly important in ischaemia imaging. • Radiation exposure of CTP is a drawback. • Iterative reconstruction (IR) allows reduction of radiation dose in unenhanced head CT. • CTP IR enables 50% dose reduction without altering objective and diagnostic quality.
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