Evidence map›Paper›PMID 24126447›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2013

Behind the cascade: analyzing spatial patterns along the HIV care continuum.

Michael G Eberhart, Baligh R Yehia, Amy Hillier, Chelsea D Voytek, Michael B Blank, Ian Frank, David S Metzger, Kathleen A Brady

Abstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Drive time to care and retention in HIV care: Rural-urban differences among Medicaid enrollees in the United States South.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michael G Eberhart*AIDS Activities Coordinating Office, Philadelphia Department of Public Health, Philadelphia, PA; †Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA; ‡Philadelphia Veterans Affairs Center for Health Equity Research and Promotion, Philadelphia, PA; §University of Pennsylvania School of Design, Philadelphia, PA; ‖Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, and ¶Division of Infectious Diseases, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA; and #Treatment Research Institute, Philadelphia, PA.
Baligh R Yehia
Amy Hillier
Chelsea D Voytek
Michael B Blank
Ian Frank
David S Metzger
Kathleen A Brady

Funding

Virus & Reservoirs CoreP30AI045008 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI FLORENCE M MOMPLAISIR · 1999 to 2026
$78.6M
Penn Mental Health AIDS Research CenterP30MH097488 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI Karine Dube · 2013 to 2026
$23.5M
The District of Columbia Developmental Center for AIDS Research (DC D-CFAR)P30AI087714 · NIAID · GEORGE WASHINGTON UNIVERSITY · PI GREENBERG, ALAN EDWARD · 2010 to 2014
$8.4M
Evaluating Patient Retention in HIV CareK23MH097647 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI YEHIA, BALIGH RAMZI · 2012 to 2013
$361k
NCHHSTP CDC HHS (PS13-130202NIAID NIH HHS 5P30AI087714NIAID NIH HHS P30 AI045008NIAID NIH HHS P30 AI087714NIAID NIH HHS P30-AI-45008NIMH NIH HHS K23 MH097647NIMH NIH HHS K23-MH097647NIMH NIH HHS P30 MH097488PHS HHS U62/003959
6 · The paper itself

Abstract

backgroundSuccessful HIV treatment as prevention requires individuals to be tested, aware of their status, linked to and retained in care, and virally suppressed. Spatial analysis may be useful for monitoring HIV care by identifying geographic areas with poor outcomes.

methodsRetrospective cohort of 1704 people newly diagnosed with HIV identified from Philadelphia's Enhanced HIV/AIDS Reporting System in 2008-2009, with follow-up to 2011. Outcomes of interest were not linked to care, not linked to care within 90 days, not retained in care, and not virally suppressed. Spatial patterns were analyzed using K-functions to identify "hot spots" for targeted intervention. Geographic components were included in regression analyses along with demographic factors to determine their impact on each outcome.

resultsOverall, 1404 persons (82%) linked to care; 75% (1059/1404) linked within 90 days; 37% (526/1059) were retained in care; and 72% (379/526) achieved viral suppression. Fifty-nine census tracts were in hot spots, with no overlap between outcomes. Persons residing in geographic areas identified by the local K-function analyses were more likely to not link to care [adjusted odds ratio 1.76 (95% confidence interval: 1.30 to 2.40)], not link to care within 90 days (1.49, 1.12-1.99), not be retained in care (1.84, 1.39-2.43), and not be virally suppressed (3.23, 1.87-5.59) than persons not residing in the identified areas.

conclusionsThis study is the first to identify spatial patterns as a strong independent predictor of linkage to care, retention in care, and viral suppression. Spatial analyses are a valuable tool for characterizing the HIV epidemic and treatment cascade.

Indexed as

Continuity of Patient CareGeographic Information SystemsSpatial AnalysisAdultAnti-Retroviral AgentsDelivery of Health CareFemaleHIV InfectionsHIV SeropositivityHumansMaleMiddle AgedPhiladelphiaViral LoadYoung AdultAnti-Retroviral Agents

Identifiers

PMID24126447
PMCPMC3891372

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.