ArticleMolecules (Basel, Switzerland)2013
Antifungal activity of Copaifera langsdorffii Desf oleoresin against dermatophytes.
Article in Molecules (Basel, Switzerland), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 35 citations in OpenAlex.
- BrazilianJournal of fungi (Basel, Switzerland) · 2020Article
- Antifungal activity of Copaíba resin oil in solution and nanoemulsion against Paracoccidioides spp.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2020Article
- Differentiation of Essential Oils Using Nanofluidic Protein Post-Translational Modification Profiling.Molecules (Basel, Switzerland) · 2019Article
- Biological Properties and Bioactive Components ofEvidence-based complementary and alternative medicine : eCAM · 2019Article
- Review
- ANTIFUNGAL POTENTIAL OF PLANT SPECIES FROM BRAZILIAN CAATINGA AGAINST DERMATOPHYTES.Revista do Instituto de Medicina Tropical de Sao Paulo · 2016Article
- Canga biodiversity, a matter of mining.Frontiers in plant science · 2014Review
- In vitro antifungal activity of organic compounds derived from amino alcohols against onychomycosis.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dermatophytoses are mycoses that affect keratinized tissues in both humans and animals. The aim of this study was to investigate the antifungal activity of the oleoresin extracted from Copaifera langsdorffii Desf. against the strains Microsporum canis ATCC 32903, Microsporum gypseum ATCC 14683, Trichophyton mentagrophytes ATCC 11481 and Trichophyton rubrum CCT 5507. The antimicrobial activity was determined by minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) values. Ketoconazole and terbinafine were used as reference drugs. The copaiba oleoresin showed moderate fungicidal activity against T. mentagrophytes ATCC 11481 (MIC and MFC = 170 μg mL-1) and weak fungicidal activity against T. rubrum CCT 5507 (MIC = 1,360 μg mL-1 and MFC = 2,720 μg mL-1). There was no activity against M. canis ATCC 32903 and M. gypseum ATCC 14683. SEM analysis revealed physical damage and morphological alterations such as compression and hyphae clustering in the structure of the fungi exposed to the action of the oleoresin. The results stimulate the achievement of in vivo assays to confirm the benefits of the application of oleoresin extracted from copaiba in the treatment of dermatophytosis, both in humans and in animals.
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