Evidence map›Paper›PMID 24126264›Full record

ReviewAnesthesiology2013

Perioperative organ injury.

Karsten Bartels, Jörn Karhausen, Eric T Clambey, Almut Grenz, Holger K Eltzschig

Open access · bronzeAbstract readReview
In one paragraph

Review in Anesthesiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 1 pooled it
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 1 synthesis or guideline pooled it, 201 citations in OpenAlex.

  1. Guideline
  2. Trial
  3. Myocardial injury in noncardiac surgery.Korean journal of anesthesiology · 2022
    Trial
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  7. Review
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  17. Review
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  20. Preventable anesthetic deaths are not the major perioperative problem.The Lancet regional health. Western Pacific · 2023
    Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Karsten Bartels* Fellow in Critical Care Medicine and Cardiothoracic Anesthesiology, † Assistant Professor of Anesthesiology, Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina. ‡ Assistant Professor of Anesthesiology, § Associate Professor of Anesthesiology, ‖ Professor of Anesthesiology, Department of Anesthesiology, University of Colorado Denver, Aurora, Colorado.
Jörn Karhausen
Eric T Clambey
Almut Grenz
Holger K Eltzschig
Society of Cardiovascular Anesthesiologists · USAmerican Heart Association · USEssex Cardiothoracic Centre · GBNational Institutes of Health · US

Funding

Trangenic Mouse Breeding CoreP01HL114457 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ZHANG, YUJIN · 2013 to 2017
$10.0M
Extracellular Adenosine During Ventilator Induced Lung InjuryR01HL092188 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI ELTZSCHIG, HOLGER K. · 2009 to 2013
$2.1M
Proton Pump Inhibitors for Perioperative Acute Kidney InjuryR01DK097075 · NIDDK · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ELTZSCHIG, HOLGER K. · 2013 to 2017
$1.7M
Hypoxia Inducible Factor in Acute Lung InjuryR01HL098294 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI ELTZSCHIG, HOLGER K. · 2011 to 2014
$1.6M
Alternative Mechanisms of Adenosine Receptor ActivationR01DK083385 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI ELTZSCHIG, HOLGER K. · 2010 to 2013
$1.2M
NHLBI NIH HHS P01 HL114457NHLBI NIH HHS R01-HL0921NHLBI NIH HHS R01 HL092188NHLBI NIH HHS R01 HL098294NHLBI NIH HHS R01-HL098294NIDDK NIH HHS R01 DK083385NIDDK NIH HHS R01-DK083385NIDDK NIH HHS R01 DK097075NIDDK NIH HHS R01-DK097075PHS HHS P0IHL114457-01
6 · The paper itself

Abstract

Despite the fact that a surgical procedure may have been performed for the appropriate indication and in a technically perfect manner, patients are threatened by perioperative organ injury. For example, stroke, myocardial infarction, acute respiratory distress syndrome, acute kidney injury, or acute gut injury are among the most common causes for morbidity and mortality in surgical patients. In the current review, the authors discuss the pathogenesis of perioperative organ injury, and provide select examples for novel treatment concepts that have emerged over the past decade. Indeed, the authors are of the opinion that research to provide mechanistic insight into acute organ injury and identification of novel therapeutic approaches for the prevention or treatment of perioperative organ injury represent the most important opportunity to improve outcomes of anesthesia and surgery.

Indexed as

Perioperative CarePerioperative PeriodGastrointestinal DiseasesHumansIntraoperative ComplicationsMyocardial InfarctionPostoperative ComplicationsRespiratory Distress SyndromeStroke

Identifiers

PMID24126264
PMCPMC3929362
OpenAlexW2169738061

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.