Evidence map›Paper›PMID 24125529›Full record

ReviewRejuvenation research2014

Caenorhabditis elegans in Chinese medicinal studies: making the case for aging and neurodegeneration.

Qiangqiang Wang, Fan Yang, Wei Guo, Ju Zhang, Lingyun Xiao, Haifeng Li, Weizhang Jia, Zebo Huang

Abstract readReview
In one paragraph

Review in Rejuvenation research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Pharmaceuticals (Basel, Switzerland) · 2024
    Article
  3. Article
  4. Exploring the Impact ofNutrients · 2023
    Article
  5. Low-Molecular-Weight Secondary Metabolites from Fungi:Molecules (Basel, Switzerland) · 2022
    Article
  6. Ginsenoside Rd protects transgenicFrontiers in pharmacology · 2022
    Article
  7. The endophytic fungusFrontiers in pharmacology · 2022
    Article
  8. Review
  9. Article
  10. Aiweixin, a Traditional Uyghur Medicinal Formula, Extends the Lifespan ofEvidence-based complementary and alternative medicine : eCAM · 2019
    Article
  11. Novel Bioactive Peptides fromMarine drugs · 2018
    Article
  12. Article
  13. Article
  14. Article
  15. Oxidative medicine and cellular longevity · 2016
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qiangqiang Wang1 Guangdong Province Key Laboratory for Biotechnology Drug Candidates, School of Biosciences and Biopharmaceutics, Guangdong Pharmaceutical University , Guangzhou, China .
Fan Yang
Wei Guo
Ju Zhang
Lingyun Xiao
Haifeng Li
Weizhang Jia
Zebo Huang

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aging is a progressive process with degenerative changes of various tissues and organs. As a classic model organism in genetics and neurobiology, Caenorhabditis elegans is also a powerful system in aging and behavioral studies and can be used at both the molecular and organismal levels to evaluate potential therapeutics for age-related neurodegeneration, owing to its short life span, relative simplicity, and high degree of experimental tractability as well as significant conservation of disease genes and signaling pathways with humans. We attempt here to summarize the use of C. elegans models in exploring traditional Chinese medicine for potential remedies against aging and neurodegeneration.

Indexed as

Medicine, Chinese TraditionalAgingAnimalsCaenorhabditis elegansLongevityNerve DegenerationOxidative Stress

Identifiers

PMID24125529
PMCPMC3995508

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.