ArticleAnnals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology2013
Association of tobacco smoke exposure and atopic sensitization.
Article in Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
10 citing papers in PubMed, 19 citations in OpenAlex.
- Active smoking effect in allergic rhinitis.The World Allergy Organization journal · 2021Article
- Vitamins A and E during Pregnancy and Allergy Symptoms in an Early Childhood-Lack of Association with Tobacco Smoke Exposure.International journal of environmental research and public health · 2018Article
- Article
- The Danish National Database for Asthma: establishing clinical quality indicators.European clinical respiratory journal · 2016Review
- Environmental tobacco smoke and the risk of eczema symptoms among school children in South Africa: a cross-sectional study.BMJ open · 2015Article
- Allergic sensitization, rhinitis, and tobacco smoke exposure in U.S. children and adolescents.International forum of allergy & rhinology · 2015Article
- The role of the early-life environment in the development of allergic disease.Immunology and allergy clinics of North America · 2015Review
- Home dust microbiota is disordered in homes of low-income asthmatic children.The Journal of asthma : official journal of the Association for the Care of Asthma · 2015Article
- Article
- Secondhand tobacco smoke exposure in low-income children and its association with asthma.Allergy and asthma proceedingsArticle
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
backgroundForty million children are regularly exposed to environmental tobacco smoke (ETS) each year, increasing their risk for premature death and middle ear and acute respiratory infections. Early life exposure to ETS also is clearly associated with wheezing. However, there is no clear understanding of the influence of ETS on the development of allergic sensitization.
objectiveTo determine the association of combined exposure to ETS and indoor allergens on IgE sensitization to aeroallergens in children.
methodsThis case-control study enrolled 116 cases and 121 controls from low-income families from Kansas City, Missouri. The adjusted odds ratio was calculated using a logistic model to assess the association between ETS and allergic sensitization using dust allergen levels as a covariate.
resultsThirty-six percent of atopic children and 39% of controls were exposed to ETS (P < .05). Unadjusted analyses showed no significant influence of ETS on IgE sensitization to indoor allergens. Logistic regression analyses also showed no significant influence of ETS on sensitization when adjusted for levels of allergens in the home dust and family history of allergic rhinitis.
conclusionThese data suggest that ETS exposure was not associated with IgE sensitization to indoor allergens, even when home allergen levels were taken into consideration. Further understanding of how components of tobacco smoke influence the immune response is necessary to interpret the disparate findings across studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.