Evidence map›Paper›PMID 24124732›Full record

ReviewJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2013

Myocardial T1 mapping and extracellular volume quantification: a Society for Cardiovascular Magnetic Resonance (SCMR) and CMR Working Group of the European Society of Cardiology consensus statement.

James C Moon, Daniel R Messroghli, Peter Kellman, Stefan K Piechnik, Matthew D Robson, Martin Ugander, Peter D Gatehouse, Andrew E Arai, Matthias G Friedrich, Stefan Neubauer and 4 more

3 registry-linked trialsOpen access · goldAbstract readReviewConsensus Statement
In one paragraph

Review in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 566 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
566citing papers in PubMed, 4 pooled it
77.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02892448 nacompletednot on this mapstarted 2016, after this paper: background citation

Cardiac MRI for Metal on Metal Orthopaedic Prostheses

TypeinterventionalSponsorOttawa Hospital Research InstituteRan2016 to 2019Enrolled35ConditionsCardiomyopathyArmsCardiac magnetic resonance imaging (CMR)
NCT03822442 completednot on this mapstarted 2019, after this paper: background citation

Cardiac MRI Increases Accuracy and Decreases Risk of Evaluation of Children With Cardiomyopathy and Cardiac Transplantation

TypeobservationalSponsorChildren's National Research InstituteRan2019 to 2025Enrolled113ConditionsHeart Failure, Cardiac Imaging Techniques, Congenital Heart Defects
NCT04128891 phase3withdrawnnot on this mapstarted 2020, after this paper: background citation

PRospectIve Study of Sacubitril/ValsarTan on MyocardIal OxygenatioN and Fibrosis in PatiEnts With Heart Failure and Preserved Ejection Fraction

TypeinterventionalSponsorFlinders UniversityRan2020 to 2024Enrolled0ConditionsHeart Failure With Preserved Ejection FractionArmsSacubitril-Valsartan
3 · Its place in the literature

Who cites it

566 citing papers in PubMed, 4 syntheses or guidelines pooled it, 1,122 citations in OpenAlex.

  1. Pooled it
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  7. Functional and structural reverse myocardial remodeling following transcatheter aortic valve replacement: a prospective cardiovascular magnetic resonance study.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2022
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  17. Age-, sex-, and segment-specific myocardial T1 and T2 reference values in a healthy cohort: a prospective single-center study.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
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  20. Review

506 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 11 institutions in 5 countries.

James C MoonThe Heart Hospital, London, UK. J.Moon@ucl.ac.uk.
Daniel R Messroghli
Peter Kellman
Stefan K Piechnik
Matthew D Robson
Martin Ugander
Peter D Gatehouse
Andrew E Arai
Matthias G Friedrich
Stefan Neubauer
Jeanette Schulz-Menger
Erik B Schelbert
Society for Cardiovascular Magnetic Resonance Imaging
Cardiovascular Magnetic Resonance Working Group of the European Society of Cardiology
John Radcliffe Hospital · GBCharité - Universitätsmedizin Berlin · DEDeutsches Herzzentrum der Charité · DEKarolinska University Hospital · SENational Heart Lung and Blood Institute · USNational Institutes of Health · USNIHR Royal Brompton Cardiovascular Biomedical Research Unit · GBUniversité de Montréal · CAUniversity College London · GBUniversity of Oxford · GBUniversity of Pittsburgh Medical Center · US

Funding

Technical Development of Diagnostic Cardiovascular MRIZIAHL004607 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI ARAI, ANDREW · 2009 to 2020
$25.3M
British Heart Foundation FS/10/40/28260British Heart Foundation FS/12/56/29723NCI NIH HHS HL004607-14CPBWellcome Trust 090532
6 · The paper itself

Abstract

Rapid innovations in cardiovascular magnetic resonance (CMR) now permit the routine acquisition of quantitative measures of myocardial and blood T1 which are key tissue characteristics. These capabilities introduce a new frontier in cardiology, enabling the practitioner/investigator to quantify biologically important myocardial properties that otherwise can be difficult to ascertain clinically. CMR may be able to track biologically important changes in the myocardium by: a) native T1 that reflects myocardial disease involving the myocyte and interstitium without use of gadolinium based contrast agents (GBCA), or b) the extracellular volume fraction (ECV)-a direct GBCA-based measurement of the size of the extracellular space, reflecting interstitial disease. The latter technique attempts to dichotomize the myocardium into its cellular and interstitial components with estimates expressed as volume fractions. This document provides recommendations for clinical and research T1 and ECV measurement, based on published evidence when available and expert consensus when not. We address site preparation, scan type, scan planning and acquisition, quality control, visualisation and analysis, technical development. We also address controversies in the field. While ECV and native T1 mapping appear destined to affect clinical decision making, they lack multi-centre application and face significant challenges, which demand a community-wide approach among stakeholders. At present, ECV and native T1 mapping appear sufficiently robust for many diseases; yet more research is required before a large-scale application for clinical decision-making can be recommended.

Indexed as

ConsensusFibrosisHeart DiseasesHumansMagnetic Resonance ImagingMyocardiumPredictive Value of Tests

Identifiers

PMID24124732
PMCPMC3854458
OpenAlexW2136811556

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.