Evidence map›Paper›PMID 24124067›Full record

ReviewAutism research : official journal of the International Society for Autism Research2013

Minimally verbal school-aged children with autism spectrum disorder: the neglected end of the spectrum.

Helen Tager-Flusberg, Connie Kasari

2 registry-linked trialsOpen access · bronzeAbstract readReview
In one paragraph

Review in Autism research : official journal of the International Society for Autism Research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 366 papers, 16 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
366citing papers in PubMed, 16 pooled it
10.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02700074 completednot on this mapstarted 2015, after this paper: background citation

ACE (Autism Center of Excellence): Brain Mechanisms for Language Processing in Adolescents With Autism Spectrum Disorder

TypeobservationalSponsorBoston University Charles River CampusRan2015 to 2019Enrolled88ConditionsAutism Spectrum DisordersArmsNo Intervention
NCT02700113 completednot on this mapstarted 2014, after this paper: background citation

Investigating Phenotypic Profiles of Minimally Verbal Children and Adolescents With ASD/Profiles of Abilities in Children and Adolescents With ASD

TypeobservationalSponsorBoston University Charles River CampusRan2014 to 2019Enrolled72ConditionsAutism Spectrum DisordersArmsNo intervention
3 · Its place in the literature

Who cites it

366 citing papers in PubMed, 16 syntheses or guidelines pooled it, 868 citations in OpenAlex.

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  7. The use of Language ENvironment Analysis in autism research: A systematic review.Autism : the international journal of research and practice · 2025
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  15. Atypical structural connectivity of language networks in autism spectrum disorder: A meta-analysis of diffusion tensor imaging studies.Autism research : official journal of the International Society for Autism Research · 2022
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306 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Helen Tager-FlusbergDepartment of Psychology, Department of Anatomy and Neurobiology, Boston University, Boston, Massachusetts.
Connie Kasari
Boston University · USUniversity of California, Los Angeles · US

Funding

Testing the efficacy of a novel intervention for minimally verbal children with P50DC013027 · NIDCD · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI SHINN-CUNNINGHAM, BARBARA · 2012 to 2016
$9.4M
Neurobehavioral Research on Infants at Risk for SLI and AutismR01DC010290 · NIDCD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI NELSON, CHARLES ALEXANDER, TAGER-FLUSBERG, HELEN · 2009 to 2020
$7.5M
1/3-Multisite RCT of Early Intervention for Spoken Communication in AutismR01MH084864 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KASARI, CONNIE L. · 2009 to 2013
$2.7M
NIDCD NIH HHS P50 DC013027NIDCD NIH HHS P50 DC 13027NIDCD NIH HHS R01 DC010290NIDCD NIH HHS R01 DC 10290-S1NIMH NIH HHS R01 MH084864PHS HHS UA3MC11055
6 · The paper itself

Abstract

It is currently estimated that about 30% of children with autism spectrum disorder remain minimally verbal, even after receiving years of interventions and a range of educational opportunities. Very little is known about the individuals at this end of the autism spectrum, in part because this is a highly variable population with no single set of defining characteristics or patterns of skills or deficits, and in part because it is extremely challenging to provide reliable or valid assessments of their developmental functioning. In this paper, we summarize current knowledge based on research including minimally verbal children. We review promising new novel methods for assessing the verbal and nonverbal abilities of minimally verbal school-aged children, including eye-tracking and brain-imaging methods that do not require overt responses. We then review what is known about interventions that may be effective in improving language and communication skills, including discussion of both nonaugmentative and augmentative methods. In the final section of the paper, we discuss the gaps in the literature and needs for future research.

Indexed as

BrainChildChild BehaviorChild Development Disorders, PervasiveEarly Intervention, EducationalEvoked PotentialsEye MovementsHumansLanguage Development DisordersMagnetoencephalographyNonverbal CommunicationVerbal Behavioralternative and augmentative communicationbehavioral intervention < interventionearly intervention < interventioneye-trackingminimally verbal ASDschool age < pediatricsspoken language

Identifiers

PMID24124067
PMCPMC3869868
OpenAlexW1909988460

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.