Evidence map›Paper›PMID 24123977›Full record

ReviewWiley interdisciplinary reviews. Nanomedicine and nanobiotechnology

Understanding engineered nanomaterial skin interactions and the modulatory effects of ultraviolet radiation skin exposure.

Samreen Jatana, Lisa A DeLouise

Abstract readReview
In one paragraph

Review in Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Samreen JatanaDepartment of Biomedical Engineering, University of Rochester, Rochester, NY, USA.
Lisa A DeLouise

Funding

Quantifying Risk Factors for Nanoparticle Contact with UVB Exposed SkinR01ES021492 · NIEHS · UNIVERSITY OF ROCHESTER · PI DELOUISE, LISA A · 2012 to 2022
$3.5M
Reagents to Enhance Detection of Raw and Biologically Transformed NanomaterialsR21OH009970 · OH · UNIVERSITY OF ROCHESTER · PI DELOUISE, LISA A · 2011 to 2012
$403k
NIEHS NIH HHS R01 ES021492NIOSH CDC HHS OH009970NIOSH CDC HHS R21 OH009970
6 · The paper itself

Abstract

The study of engineered nanomaterials for the development of technological applications, nanomedicine, and nano-enabled consumer products is an ever-expanding discipline as is the concern over the impact of nanotechnology on human environmental health and safety. In this review, we discuss the current state of understanding of nanomaterial skin interactions with a specific emphasis on the effects of ultraviolet radiation (UVR) skin exposure. Skin is the largest organ of the body and is typically exposed to UVR on a daily basis. This necessitates the need to understand how UVR skin exposure can influence nanomaterial skin penetration, alter nanomaterial systemic trafficking, toxicity, and skin immune function. We explore the unique dichotomy that UVR has on inducing both deleterious and therapeutic effects in skin. The subject matter covered in this review is broadly informative and will raise awareness of potential increased risks from nanomaterial skin exposure associated with specific occupational and life style choices. The UVR-induced immunosuppressive response in skin raises intriguing questions that motivate future research directions in the nanotoxicology and nanomedicine fields.

Indexed as

NanomedicineNanostructuresSkinUltraviolet RaysAnimalsCells, CulturedHumansMice

Identifiers

PMID24123977
PMCPMC3865219

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.