ReviewAmerican journal of medical genetics. Part A2013
Developmental disease and cancer: biological and clinical overlaps.
Review in American journal of medical genetics. Part A, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Cancer prevention and screening for people with intellectual disabilities in Europe: a systematic review and recommendations for policy and practice.Frontiers in public health · 2026Pooled it
- Cancer prevalence and care disparities among individuals with intellectual disabilities: a cross-sectional pan-cancer analysis.ESMO real world data and digital oncology · 2025Article
- The Elephant and the Spandrel.Evolution, medicine, and public health · 2025Article
- ASXL1 truncating variants in BOS and myeloid leukemia drive shared disruption of Wnt-signaling pathways but have differential isoform usage of RUNX3.BMC medical genomics · 2024Article
- Article
- [Cancer in people with an intellectual disability in Germany: prevalence, genetics, and care situation].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2024Review
- Onco-Breastomics: An Eco-Evo-Devo Holistic Approach.International journal of molecular sciences · 2024Review
- Assessing cancer in people with profound and multiple disabilities.BMC cancer · 2023Article
- Targeting the Retinoic Acid Pathway to Eradicate Cancer Stem Cells.International journal of molecular sciences · 2023Review
- Association of Pathogenic Variants in Hereditary Cancer Genes With Multiple Diseases.JAMA oncology · 2022Article
- Convergent Usage of Amino Acids in Human Cancers as A Reversed Process of Tissue Development.Genomics, proteomics & bioinformatics · 2022Article
- Extracellular Vesicles in Premature Aging and Diseases in Adulthood Due to Developmental Exposures.Aging and disease · 2021Review
- Cancer: An unknown territory; rethinking before going ahead.Genes & diseases · 2021Review
- Toxic and Teratogenic Effects of Prenatal Alcohol Exposure on Fetal Development, Adolescence, and Adulthood.International journal of molecular sciences · 2021Review
- Augmented BMP signaling commits cranial neural crest cells to a chondrogenic fate by suppressing autophagic β-catenin degradation.Science signaling · 2021Article
- OncogenicProceedings of the National Academy of Sciences of the United States of America · 2019Article
- A genome-wide analysis of colorectal cancer in a child with Noonan syndrome.Pediatric blood & cancer · 2018Article
- A De Novo FOXP1 Truncating Mutation in a Patient Originally Diagnosed as C Syndrome.Scientific reports · 2018Article
- Progress in Rare Diseases Research 2010-2016: An IRDiRC Perspective.Clinical and translational science · 2018Review
- Mosaic Activating Mutations in FGFR1 Cause Encephalocraniocutaneous Lipomatosis.American journal of human genetics · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Numerous parallelisms exist between development and cancer. In this article, I review some of the founding ideas linking development and cancer, and highlight clinical conditions exhibiting features of both developmental derangement and cancer predisposition, including cohesinopathies, rasopathies, phakomatoses, Proteus syndrome and other overgrowth disorders, recessive chromosome breakage syndromes, and dominant hereditary cancer syndromes. I suggest that these disorders encompass a continuous spectrum spanning clinical genetics and clinical oncology, and derive some general implications that might be useful in the future for the treatment of these diseases.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.