Evidence map›Paper›PMID 24123823›Full record

ArticleJournal of bacteriology2013

Disconnecting in vitro ESX-1 secretion from mycobacterial virulence.

Patricia A DiGiuseppe Champion

Abstract readComment
In one paragraph

Article in Journal of bacteriology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Proteo-genetic analysis reveals clear hierarchy of ESX-1 secretion inProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. WhiB6 regulation of ESX-1 gene expression is controlled by a negative feedback loop inProceedings of the National Academy of Sciences of the United States of America · 2017
    Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Patricia A DiGiuseppe ChampionEck Institute for Global Health, Center for Rare and Neglected Diseases, Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana, USA.

Funding

Vaccines and Therapies Against BotulismU54AI057153 · NIAID · UNIVERSITY OF CHICAGO · PI SCHNEEWIND, OLAF · 2003 to 2013
$87.6M
Role of N-alpha acetylation in mycobacterial secretion and virulenceR01AI106872 · NIAID · UNIVERSITY OF NOTRE DAME · PI CHAMPION, PATRICIA A · 2013 to 2024
$4.2M
Comprehensive Identification of the Genetic Requirements for ESX-1 SecretionR21AI092484 · NIAID · UNIVERSITY OF NOTRE DAME · PI CHAMPION, PATRICIA A · 2011 to 2012
$413k
NIAID NIH HHS R01 AI106872NIAID NIH HHS R21 AI092484NIAID NIH HHS U54 AI057153
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAntigens, BacterialBacterial ProteinsHumansMembrane Transport ProteinsMycobacterium tuberculosisAntigens, BacterialBacterial ProteinsCFP-10 protein, Mycobacterium tuberculosisESAT-6 protein, Mycobacterium tuberculosisMembrane Transport Proteins

Identifiers

PMID24123823
PMCPMC3889606

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.