ArticleJournal of experimental botany2013
FOUR LIPS and MYB88 conditionally restrict the G1/S transition during stomatal formation.
Article in Journal of experimental botany, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Increased Temperatures Promote Fruit Enlargement Through Cellular and Transcriptomic Changes in Raspberries (Plants (Basel, Switzerland) · 2026Article
- The Characterization of R2R3-MYB Genes inBiomolecules · 2023Article
- Maize LOST SUBSIDIARY CELL encoding a large subunit of ribonucleotide reductase is required for subsidiary cell development and plant growth.Journal of experimental botany · 2023Article
- Identification of the passion fruit (Frontiers in plant science · 2023Article
- Plant CDKs-Driving the Cell Cycle through Climate Change.Plants (Basel, Switzerland) · 2021Review
- Expression Pattern and Functional Analyses ofFrontiers in plant science · 2021Article
- Article
- Lineage- and stage-specific expressedDevelopment (Cambridge, England) · 2018Article
- Co-expression and Transcriptome Analysis ofFrontiers in plant science · 2018Article
- Genome-wide characterization and expression analysis of MYB transcription factors in Gossypium hirsutum.BMC genetics · 2016Article
- Quantitative analysis of microtubule orientation in interdigitated leaf pavement cells.Plant signaling & behavior · 2015Article
- Requirement for A-type cyclin-dependent kinase and cyclins for the terminal division in the stomatal lineage of Arabidopsis.Journal of experimental botany · 2014Article
- Signaling to stomatal initiation and cell division.Frontiers in plant science · 2014Review
Corrections and comments
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Authors and funding
4 authors.
Funding
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Abstract
Consistent with their valve-like function in shoot-atmosphere gas exchange, guard cells are smaller than other epidermal cells and usually harbour 2C DNA levels in diploid plants. The paralogous Arabidopsis R2R3 MYB transcription factors, FOUR LIPS and MYB88, ensure that stomata contain just two guard cells by restricting mitosis. The loss of both FLP and MYB88 function in flp myb88 double mutants induces repeated mitotic divisions that lead to the formation of clusters of stomata in direct contact. By contrast, CYCLIN DEPENDENT KINASE B1 function is required for the symmetric division that precedes stomatal maturation. It was found that blocking mitosis by chemically disrupting microtubules or by the combined loss of FLP/MYB88 and CDKB1 function, causes single (undivided) guard cells (sGCs) to enlarge and attain mean DNA levels of up to 10C. The loss of both FLP and CDKB1 function also dramatically increased plastid number, led to the formation of multiple nuclei in GCs, altered GC and stomatal shape, and disrupted the fate of lineage-specific stem cells. Thus, in addition to respectively restricting and promoting symmetric divisions, FLP and CDKB1 together also conditionally restrict the G1/S transition and chloroplast and nuclear number, and normally maintain fate and developmental progression throughout the stomatal cell lineage.
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