ArticleClinical cardiology2014
Lower admission hemoglobin levels are associated with longer symptom duration in acute ST-elevation myocardial infarction.
Article in Clinical cardiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- The predictive value of machine learning for mortality risk in patients with acute coronary syndromes: a systematic review and meta-analysis.European journal of medical research · 2023Pooled it
- Effect of Four Hemoglobin Transfusion Threshold Strategies in Patients With Acute Myocardial Infarction and Anemia : A Target Trial Emulation Using MINT Trial Data.Annals of internal medicine · 2024Trial
- The AHEAD-NLR score: a novel inflammatory-comorbidity integrated tool for predicting long-term mortality in patients with heart failure after acute myocardial infarction.Scientific reports · 2026Article
- Association between time-varying weighted hemoglobin and all-cause mortality in patients with acute myocardial infarction-related cardiogenic shock.Frontiers in cardiovascular medicine · 2025Article
- The Incidence and Risk Factors of Acute Myocardial Infarction Among Patients with Gastrointestinal bleeding: A Retrospective Study.International journal of general medicine · 2023Article
- Observational
- Acute Anemia and Myocardial Infarction.Cureus · 2021Review
- Incremental Prognostic Value of Anemia in Acute Coronary Syndrome from A Rural Hospital in India.Global heart · 2020Article
- Incidence and outcomes of early left ventricular thrombus following ST-elevation myocardial infarction treated with primary percutaneous coronary intervention.Clinical research in cardiology : official journal of the German Cardiac Society · 2017Article
- Article
- Anemia and Acute Coronary Syndrome: Time for Intervention Studies.Journal of the American Heart Association · 2016Article
- Acute kidney injury among ST elevation myocardial infarction patients treated by primary percutaneous coronary intervention: a multifactorial entity.Journal of nephrology · 2016Review
- High sensitive C-reactive protein and the risk of acute kidney injury among ST elevation myocardial infarction patients undergoing primary percutaneous intervention.Clinical and experimental nephrology · 2015Article
- Anemia and Inflammation in ST-Segment Elevation Myocardial Infarction.The American journal of the medical sciences · 2015Article
- Renal impairment according to acute kidney injury network criteria among ST elevation myocardial infarction patients undergoing primary percutaneous intervention: a retrospective observational study.Clinical research in cardiology : official journal of the German Cardiac Society · 2014Observational
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAn acute-phase response in patients with acute myocardial infarction could contribute to the development of anemia. HYPOTHESIS: An association may exist between symptom duration, hemoglobin (Hb) concentration and serum C-reactive protein (CRP) values in patients presenting to an emergency department (ED) with acute ST-segment elevation myocardial infarction (STEMI).
methodsA retrospective analysis was conducted on consecutive male STEMI patients who were admitted to our medical center's ED from January 2008 to November 2012 and had presented within the first 12 hours after the onset of chest pain. Hemoglobin concentration and serum CRP levels were determined from blood samples taken prior to any drug or fluid administration. Analyses of variance were used to determine interactions between selected time-to-presentation cutoffs and admission Hb and CRP concentrations. Patients with other reasons known to cause elevation of inflammatory markers, anemia, or bleeding diathesis were excluded.
resultsThe study population comprised 718 patients whose mean age was 61 ± 12 years (range, 27-96 years). Blood was drawn for Hb and CRP measurements directly upon admission. Patients who presented to the ED within 3 hours of symptom onset had higher Hb concentrations (P = 0.048) and lower serum CRP levels (P < 0.001) compared with those who presented after a longer interval from symptom onset.
conclusionsLonger symptom duration is associated with a lower admission Hb level and an early rise in the CRP level of male patients with acute STEMI.
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