ArticleAmerican journal of hematology2014
Effect of race on outcomes after allogeneic hematopoietic cell transplantation for severe aplastic anemia.
Article in American journal of hematology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 28 citations in OpenAlex.
- A trial of unrelated donor marrow transplantation for children with severe sickle cell disease.Blood · 2016Trial
- Evidence- and opinion-based consensus from Delphi round 1 of the Asian aplastic anemia recommendation development.International journal of hematology · 2026Article
- Chronic graft-versus-host disease.Nature reviews. Disease primers · 2026Review
- Differences in Acute Graft-Versus-Host Disease (GVHD) Severity and Its Outcomes Between Black and White Patients.Transplantation and cellular therapy · 2024Article
- Long-term Survival after Hematopoietic Cell Transplant for Sickle Cell Disease Compared to the United States Population.Transplantation and cellular therapy · 2022Article
- Parental limited English proficiency in pediatric stem cell transplantation: Clinical impact and health care utilization.Pediatric blood & cancer · 2021Article
- Racial disparities in hematopoietic stem cell transplant: a systematic review of the literature.Stem cell investigation · 2021Review
- Abatacept is effective as GVHD prophylaxis in unrelated donor stem cell transplantation for children with severe sickle cell disease.Blood advances · 2020Article
- Comparison of characteristics and outcomes of late acute and NIH chronic GVHD between Japanese and white patients.Blood advances · 2019Article
- Patient features and survival of pediatric aplastic anemia in the USA: a large institution experience.Journal of public health (Oxford, England) · 2019Article
- Aplastic Anemia.The New England journal of medicine · 2018Review
- Racial differences in allogeneic hematopoietic cell transplantation outcomes among African Americans and whites.Bone marrow transplantation · 2015Article
- Advances in unrelated and alternative donor hematopoietic cell transplantation for nonmalignant disorders.Current opinion in pediatrics · 2015Review
Corrections and comments
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Authors and funding
9 authors at 6 institutions in 1 country.
Funding
Abstract
We compared outcomes after hematopoietic cell transplantation in patients of African American (n = 84) and Caucasian (n = 215) descent with severe aplastic anemia. African Americans and Caucasians were matched for age, donor-recipient human leukocyte antigen match, graft type, and transplantation year. The median follow-up of surviving patients was 5 years. In multivariate analysis, overall mortality risks were higher for African Americans compared to Caucasians (relative risk 1.73, P = 0.01). The 5-year probabilities of overall survival adjusted for interval from diagnosis to transplantation, and performance score was 58% for African Americans and 73% for Caucasians. The day-100 cumulative incidence of grade III-IV, but not grade II-IV acute graft-versus-host disease (GVHD), was higher in African Americans compared to Caucasians (29% vs. 13%, P = 0.006). Although the 5-year cumulative incidence of chronic GVHD was not significantly different between the racial groups, African Americans were more likely to have extensive chronic GVHD compared to Caucasians (72% vs. 49%, P = 0.06). Survival differences between Caucasians and African Americans can be attributed to multiple factors. Our data suggest that some of the observed survival differences between Caucasians and African Americans may be explained by higher rates of acute GVHD and severity of chronic GVHD.
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Registered trials
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