Evidence map›Paper›PMID 24122796›Full record

ArticleThe Journal of pathology2014

Dendritic cells in IBD pathogenesis: an area of therapeutic opportunity?

Jennifer Bates, Lauri Diehl

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of pathology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 57 citations in OpenAlex.

  1. Review
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  8. CaCells · 2024
    Review
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  20. Clinical Use ofFrontiers in immunology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jennifer BatesGenentech, Inc, South San Francisco, CA, 94080, USA.
Lauri Diehl

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dysfunction of the mucosal immune system plays an important role in inflammatory bowel disease (IBD) pathogenesis. Dendritic cells are emerging as central players based on both our increasing understanding of how genetic susceptibility impacts the mucosal immune system and the key role of dendritic cells in regulating response to gut microflora. We discuss areas of therapeutic opportunity in this evolving landscape.

Indexed as

Drug DiscoveryAnimalsAnti-Inflammatory AgentsColitis, UlcerativeCrohn DiseaseDendritic CellsGastrointestinal AgentsHumansImmunity, MucosalIntestinesMiceMolecular Targeted TherapyAnti-Inflammatory AgentsGastrointestinal AgentscolitisCrohn's diseasedendritic cellinflammationinflammatory bowel diseasemucosal immunity

Identifiers

PMID24122796
PMCPMC4285849
OpenAlexW1480052323

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.