Trial reportSurgical endoscopy2014
Short-term results of a randomized study between laparoscopic and open surgery in elderly colorectal cancer patients.
Trial report in Surgical endoscopy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 9 syntheses or guidelines pooled it, 87 citations in OpenAlex.
- EAES/SAGES evidence-based recommendations and expert consensus on optimization of perioperative care in older adults.Surgical endoscopy · 2024Guideline
- Mid- and low-rectal cancer: laparoscopic vs open treatment-short- and long-term results. Meta-analysis of randomized controlled trials.International journal of colorectal disease · 2022Pooled it
- Laparoscopic versus open hepatectomy for malignant liver tumours in the elderly: systematic review and meta-analysis.Updates in surgery · 2021Pooled it
- Pooled it
- Laparoscopic liver resection in elderly patients: systematic review and meta-analysis.Surgical endoscopy · 2019Pooled it
- A meta-analysis of laparoscopic surgery versus conventional open surgery in the treatment of colorectal cancer.Medicine · 2019Pooled it
- Induced Bias Due to Crossover Within Randomized Controlled Trials in Surgical Oncology: A Meta-regression Analysis of Minimally Invasive versus Open Surgery for the Treatment of Gastrointestinal Cancer.Annals of surgical oncology · 2018Pooled it
- Is laparoscopic colorectal surgery beneficial for elderly patients? A systematic review and meta-analysis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2015Pooled it
- Chewing gum for postoperative recovery of gastrointestinal function.The Cochrane database of systematic reviews · 2015Pooled it
- Long-term results of a randomized study comparing open surgery and laparoscopic surgery in elderly colorectal cancer patients (Eld Lap study).Surgical endoscopy · 2021Trial
- Midterm follow-up of a randomized trial of open surgery versus laparoscopic surgery in elderly patients with colorectal cancer.Surgical endoscopy · 2017Trial
- Surgical treatment strategy for elderly patients with esophageal cancer in the new era: a narrative review.Surgery today · 2025Review
- Article
- A retrospective study on influencing factors of postoperative hospital stay and development of a predictive scoring model for elderly patients (≥70 years) with colorectal cancer undergoing laparoscopic radical resection.Frontiers in surgery · 2025Article
- A retrospective cohort study of the effect of sugammadex versus neostigmine on postoperative gastrointestinal motility in open colorectal surgical procedures.Surgery in practice and science · 2024Article
- Impact of laparoscopic surgery on short-term and long-term outcomes in elderly obese patients with colon cancer.Annals of gastroenterological surgery · 2023Article
- How to prevent postoperative ileus in colorectal surgery? a systematic review.Annals of medicine and surgery (2012) · 2023Review
- Benefits of minimally invasive surgery for rectal cancer in older adults compared with younger adults: a retrospective study.Journal of robotic surgery · 2023Article
- Outcomes of open vs laparoscopic vs robotic vs transanal total mesorectal excision (TME) for rectal cancer: a network meta-analysis.Techniques in coloproctology · 2023Review
- Robotic versus laparoscopic colorectal surgery in elderly patients in terms of recovery time: a monocentric experience.Journal of robotic surgery · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn surgical treatment of elderly patients, securing the safety of surgery and radical cure must be balanced. Our purpose was to verify the safety and validity of laparoscopic surgery for the treatment of colorectal cancer in elderly patients.
methodsPatients with cTis–T4a colorectal cancer who were 75 years or older were randomized to receive open or laparoscopic surgery. Exclusion criteria were patients who had a bulky tumor, rectal cancer that required pelvic side wall lymphadenectomy, and history of colon resection. Patients were divided according to tumor location (right colon, left colon, and rectum). The short-term outcomes were compared between the two groups.
resultsOne hundred patients (right 43, left 28, and rectum 29) were registered in each group from August 2008 to August 2012. There were no differences in patient characteristics between the two groups. Three patients were converted from laparoscopic to open, because of bleeding, excision of peritoneum metastasis, and patient’s desire, respectively. In the short-term results (open:laparoscopic), there were significant differences in the rates of complications (36:23 %) and ileus (12:4 %), amount of blood loss (157:63 mL), and duration of surgery (150:172 min). There were no significant differences in the pathological margins, and the number of dissected lymph nodes. In the subgroup analysis according to the tumor location, there were significant differences in the rate of complications (39.4:22.5 %), amount of blood loss (135:42 mL), duration of surgery (139:160 min), and length of postoperative stay (13.0:10.0 days) in the colon cancer. There were no significant differences in short-term results in the rectal cancer.
conclusionsLaparoscopic surgery in elderly colorectal cancer patients did not result in a difference in radical cure compared with open surgery, and the short-term results except the duration of surgery were excellent. It is an effective procedure for elderly patients with colorectal cancer, especially colon cancer.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.