ArticleMarine biotechnology (New York, N.Y.)2014
Transcriptome profiling reveals insight into distinct immune responses to Aeromonas salmonicida in gill of two rainbow trout strains.
Article in Marine biotechnology (New York, N.Y.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 60 citations in OpenAlex.
- Analysis of Striped Bass (Morone saxatilis) and White Bass (M. chrysops) Splenic Transcriptome Following Streptococcus iniae Infection.Marine biotechnology (New York, N.Y.) · 2025Article
- Pleiotropic Role of Rainbow Trout CXCRs in Response to Disease and Environment: Insights from Transcriptional Signatures and Structure Analysis.Biomolecules · 2024Article
- Molecular Characterization and Expression Analysis of IL-10 and IL-6 in Channel Catfish (Pathogens (Basel, Switzerland) · 2023Article
- Multi-Organ Transcriptome Response of Lumpfish (Microorganisms · 2022Article
- Variations in Rainbow Trout Immune Responses againstBiology · 2022Article
- Whole-genome association study searching for QTL for Aeromonas salmonicida resistance in rainbow trout.Scientific reports · 2021Article
- Transcriptome profiling of immune response to Yersinia ruckeri in spleen of rainbow trout (Oncorhynchus mykiss).BMC genomics · 2021Article
- The Dynamic Immune Response of Yellow Catfish (Frontiers in immunology · 2021Article
- Comparative Analysis of the Transcriptome and Distribution of Putative SNPs in Two Rainbow Trout (Genes · 2020Article
- GWAS Analysis Indicated Importance of NF-κB Signaling Pathway in Host Resistance Against Motile Aeromonas Septicemia Disease in Catfish.Marine biotechnology (New York, N.Y.) · 2019Article
- Spleen and head kidney differential gene expression patterns in trout infected with Lactococcus garvieae correlate with spleen granulomas.Veterinary research · 2019Article
- At Least Two Genes Encode Many Variants of Irak3 in Rainbow Trout, but Neither the Full-Length Factor Nor Its Variants Interfere Directly With the TLR-Mediated Stimulation of Inflammation.Frontiers in immunology · 2019Article
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- Identification of Immune-Related Genes and Development of SSR/SNP Markers from the Spleen Transcriptome of Schizothorax prenanti.PloS one · 2016Article
- Impact of Thermal Stress on Kidney-Specific Gene Expression in Farmed Regional and Imported Rainbow Trout.Marine biotechnology (New York, N.Y.) · 2015Article
- Integration of Transcriptomic and Proteomic Approaches Provides a Core Set of Genes for Understanding of Scallop Attachment.Marine biotechnology (New York, N.Y.) · 2015Article
- Microarray Analysis of Immunity Against WSSV in Response to Injection of Non-specific Long dsRNA in Kuruma Shrimp, Marsupenaeus japonicus.Marine biotechnology (New York, N.Y.) · 2015Article
- An Enriched European Eel Transcriptome Sheds Light upon Host-Pathogen Interactions with Vibrio vulnificus.PloS one · 2015Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The fish gills represent a crucial organ for the communication with the aquatic environment. Transcriptional changes in gills of two hatchery rainbow trout strains in response to injection with the potent pathogen Aeromonas salmonicida were detected by global gene expression profiling using a 4×44K oligonucleotide microarray. Emphasis was placed on "day 3 postinfection" representing a decisive time point for the resolution of inflammation. The comparison of features and pathways differentially regulated in branchial tissues revealed that the local breeding strain BORN and imported American rainbow trout apply common and specific immune strategies. In gills of infected BORN trout, we observed a dynamic regulation of genes controlling NF-κB pathways and the induction of factors promoting the development of myeloid cells, whereas an increased expression of lysozyme and immunoglobulin genes was obvious in gills of infected import trout. In order to prove the relevance of the array-predicted candidates as well as well-known immune genes for gill immunity, a subsequent in vitro experiment was conducted. Altogether, we uncovered dynamic but moderate changes in the expression of a broad range of immune-relevant features implying the gill's involvement in pathogen defense strategies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.