SynthesisEuropean radiology2014
Diagnostic accuracy of digital breast tomosynthesis versus digital mammography for benign and malignant lesions in breasts: a meta-analysis.
Synthesis in European radiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Performance of digital breast tomosynthesis with digital mammography for detecting breast cancer in the diagnostic setting: a meta-analysis.Clinical and experimental medicine · 2025Pooled it
- Diagnostic performance of tomosynthesis plus synthetic mammography versus full-field digital mammography with or without tomosynthesis in breast cancer screening: A systematic review and meta-analysis.International journal of cancer · 2025Pooled it
- Accuracy of Digital Breast Tomosynthesis for Detecting Breast Cancer in the Diagnostic Setting: A Systematic Review and Meta-Analysis.Korean journal of radiology · 2021Pooled it
- Diagnostic Accuracy of Nipple Aspirate Fluid Cytology in Asymptomatic Patients: A Meta-analysis and Systematic Review of the Literature.Annals of surgical oncology · 2021Pooled it
- Accuracy and Effectiveness of Mammography versus Mammography and Tomosynthesis for Population-Based Breast Cancer Screening: A Systematic Review and Meta-Analysis.Scientific reports · 2020Pooled it
- Digital breast tomosynthesis for breast cancer detection: a diagnostic test accuracy systematic review and meta-analysis.European radiology · 2020Pooled it
- Performance of one-view breast tomosynthesis as a stand-alone breast cancer screening modality: results from the Malmö Breast Tomosynthesis Screening Trial, a population-based study.European radiology · 2016Trial
- Characterisation of microcalcification clusters on 2D digital mammography (FFDM) and digital breast tomosynthesis (DBT): does DBT underestimate microcalcification clusters? Results of a multicentre study.European radiology · 2015Trial
- Deep Learning in Digital Breast Tomosynthesis: Current Status, Challenges, and Future Trends.MedComm · 2025Review
- Early detection of breast cancer through the diagnosis of Nipple Aspirate Fluid (NAF).Clinical proteomics · 2024Review
- Diagnostic yield of dental radiography and digital tomosynthesis for the identification of anatomic structures in dogs.Frontiers in veterinary science · 2024Article
- Article
- Breast cancer detection with upstream data fusion, machine learning, and automated registration: initial results.Journal of medical imaging (Bellingham, Wash.) · 2023Article
- Digital Tomosynthesis versus Conventional Radiography for Evaluating Osteonecrosis of the Femoral Head.Korean journal of radiology · 2021Article
- A novel panel of blood-based microRNAs capable of discrimination between benign breast disease and breast cancer at early stages.RNA biology · 2021Article
- Malignancy Upgrade Rates of Radial Sclerosing Lesions at Breast Cancer Screening.Radiology. Imaging cancer · 2021Article
- Effect of x-ray energy on the radiological image quality in propagation-based phase-contrast computed tomography of the breast.Journal of medical imaging (Bellingham, Wash.) · 2021Article
- Application of deep learning in the detection of breast lesions with four different breast densities.Cancer medicine · 2021Article
- Diagnostic accuracy of contrast-enhanced digital mammography in breast cancer detection in comparison to tomosynthesis, synthetic 2D mammography and tomosynthesis combined with ultrasound in women with dense breast.The British journal of radiology · 2021Article
- Utilization and Cost of Mammography Screening Among Commercially Insured Women 50 to 64 Years of Age in the United States, 2012-2016.Journal of women's health (2002) · 2020Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the diagnostic performance of digital breast tomosynthesis (DBT) and digital mammography (DM) for benign and malignant lesions in breasts.
methodsDocument retrieval was conducted on PubMed, EMBASE, the Cochrane Library, Web of Science and Chinese Biomedical Literature Database, etc., from 1950 to June 2013. Metadisc1.4 software was used to analyse the pooled sensitivity, specificity, diagnostic odds ratio (DOR), and positive and negative likelihood ratio. The heterogeneity was assessed using forest plots and the inconsistency index (I(2)). Before statistical comparison, the area under (AUC) the summary receiver-operating characteristic curve (SROC) of two different diagnostic methods was calculated respectively.
resultsA total of seven studies involving 2,014 patients and 2,666 breast lesions were included. Compared with the gold standard (histological results), the pooled sensitivity and specificity of DBT were 90.0% and 79.0%, and for DM they were 89.0% and 72.0%, respectively. The pooled positive likelihood ratio of DBT and DM was 3.50 and 2.83; the pooled negative likelihood ratio of DBT and DM was 15% and 18%; the pooled DOR for DBT and DM was 26.04 and 16.24, respectively.
conclusionsDigital breast tomosynthesis has a higher sensitivity and specificity in breast diagnosis than digital mammography. KEY POINTS: • Digital breast tomosynthesis has high sensitivity and specificity in breast diagnosis.• DBT appears to have superior diagnostic accuracy relative to digital mammography. • DBT images were captured at a lower dose than 2D images. • DBT displays abnormal features of lesions more clearly than DM. • Digital breast tomosynthesis could become the first choice for assessing breast lesions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.