ArticleEndocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
Frax prediction without BMD for assessment of osteoporotic fracture risk.
Article in Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 64 citations in OpenAlex.
- Advancing fracture risk prediction: established assessment tools and emerging HR-pQCT-based approaches.Frontiers in endocrinology · 2026Review
- Community-based evaluation of Saudi FRAX with and without BMD in Riyadh, Saudi Arabia.Archives of osteoporosis · 2025Article
- Comparative effectiveness of denosumab vs alendronate among postmenopausal women with osteoporosis.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024Article
- Age-Dependent Association of Height Loss with Incident Fracture Risk in Postmenopausal Korean Women.Endocrinology and metabolism (Seoul, Korea) · 2023Article
- Future Fracture Risk in Upper Extremity Fracture and Non-Fracture Patients.Hand (New York, N.Y.) · 2023Article
- FRAX calculation with and without bone mineral density for assessment of osteoporotic fracture risk in patients of rheumatic disease: a cross-sectional study.Annals of medicine and surgery (2012) · 2023Article
- Cross-sectional osteoporotic risk prediction with the FRAX without BMD in male and female patients attending OPD in a community health center of Bihar.Journal of family medicine and primary care · 2022Article
- Race and Age Impact Osteoporosis Screening Rates in Women Prior to Hip Fracture.Archives of osteoporosis · 2022Article
- [Value of a nomogram model based on IDEAL-IQ for predicting early bone mass loss].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2021Article
- The usefulness of trabecular bone score in patients with ankylosing spondylitis.The Korean journal of internal medicine · 2021Article
- FRAX-based osteoporosis treatment guidelines for resource-poor settings in India.Archives of osteoporosis · 2021Article
- FRAX score with and without bone mineral density: a comparison and factors affecting the discordance in osteoporosis treatment in Thais.Archives of osteoporosis · 2021Article
- Bone health assessment in clinical practice is infrequenty performed in patients with chronic pancreatitis.Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] · 2020Article
- Utility of FRAX (fracture risk assessment tool) in primary care and family practice setting in India.Journal of family medicine and primary care · 2019Article
- Prevalence and Fracture Risk of Osteoporosis in Patients with Rheumatoid Arthritis: A Multicenter Comparative Study of the FRAX and WHO Criteria.Journal of clinical medicine · 2018Article
- Limited Osteoporosis Screening Effectiveness Due to Low Treatment Rates in a National Sample of Older Men.Mayo Clinic proceedings · 2018Observational
- Competing Risks of Fracture and Death in Older Adults with Chronic Kidney Disease.Journal of the American Geriatrics Society · 2018Article
- FRAX Calculated without BMD Resulting in a Higher Fracture Risk Than That Calculated with BMD in Women with Early Breast Cancer.Journal of osteoporosis · 2018Article
- The Effectiveness of Osteoporosis Screening and Treatment in the Midwest.Geriatric orthopaedic surgery & rehabilitation · 2018Article
- FRAX Prediction With and Without Bone Mineral Density Testing.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2017Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo compare Fracture Risk Assessment Tool (FRAX) calculations with and without bone mineral density (BMD) in predicting the 10-year probability of hip and major osteoporotic fractures (MOF).
methodsA cross-sectional review of patients requiring screening for osteoporosis as part of their routine medical care was conducted. Postmenopausal women and men over 50 years of age who were never diagnosed with osteoporosis or treated with U.S. Food and Drug Administration-approved agents for osteoporosis were included. Height, weight, FRAX questionnaire, femoral neck BMD, and T-score data were obtained. FRAX scores with BMD (FRAX/BMD) and without BMD (FRAX) were calculated. Subjects were separated on the basis of identical and different treatment recommendations. Fracture risk factors were compared between groups using simple Student's t test analysis of numerical variables and Fisher's exact test analysis of binary variables.
resultsOf 151 total subjects, 127 (84%) had identical fracture risk predictions with or without BMD included in the FRAX calculation. Thirty subjects met treatment criteria and 97 did not, but the FRAX prediction was the same with risk factors alone or with risk factors plus BMD. Age was the only risk factor that was significantly different between those with identical and different predictions (median age, 64.42 and 76.25 years, respectively; P<.001).
conclusionIn most cases, FRAX alone provides the same prediction as FRAX with BMD. Younger age is more indicative of an identical prediction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.