ArticleAmerican journal of obstetrics and gynecology2014
Clinical care for opioid-using pregnant and postpartum women: the role of obstetric providers.
Article in American journal of obstetrics and gynecology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03098407 (A Pilot Randomized Comparative Effectiveness Clinical Trial of Buprenorphine vs. Methadone for the Treatment of Opioid Dependence in Pregnancy.), which is not on this map. Cited by 46 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Pilot Randomized Comparative Effectiveness Clinical Trial of Buprenorphine vs. Methadone for the Treatment of Opioid Dependence in Pregnancy.
Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it, 118 citations in OpenAlex.
- Guideline
- The effect of prenatal alcohol co-exposure on neonatal abstinence syndrome in infants born to mothers in opioid maintenance treatment.The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2016Trial
- Prenatal drug use criminalization and health system avoidance: Evidence from births in Alabama, South Carolina, and Tennessee, 1989-2019.Social science & medicine (1982) · 2025Article
- Hospital Care for Pregnant Persons With OUD Review.American journal of medicine open · 2025Review
- Opioid Use Disorder Cascade of Care Among People Who Experienced Perinatal Incarceration: A Qualitative Study.Substance use & addiction journal · 2025Article
- The Psychiatrist's Role in Treating Perinatal Opioid Use Disorder and Reducing Maternal Mortality.Focus (American Psychiatric Publishing) · 2024Review
- Screening and Brief Interventions for Alcohol Use During Pregnancy: Practices Among US Primary Care Clinicians, DocStyles 2019.Preventing chronic disease · 2023Article
- Saving time, signaling trust: Using the PROMOTE self-report screening instrument to enhance prenatal care quality and therapeutic relationships.PEC innovation · 2022Article
- Listening to women and pregnant and postpartum people: Qualitative research to inform opioid use disorder treatment for pregnant and postpartum people.Drug and alcohol dependence reports · 2022Article
- Categorization of Opioid Use Among Pregnant People and Association With Overdose or Death.JAMA network open · 2022Article
- Medications for opioid use disorder during pregnancy: Access and continuity in a state women's prison facility, 2016-2019.Drug and alcohol dependence · 2022Article
- Differences in outpatient, emergency, and inpatient use among pregnant women with a substance-related diagnosis.American journal of obstetrics & gynecology MFM · 2022Article
- Physician Referrals During Prenatal Care.Maternal and child health journal · 2021Article
- Health care and social justice implications of incarceration for pregnant people who use drugs.International review of psychiatry (Abingdon, England) · 2021Review
- Scoping Review of the Associations Between Perinatal Substance Use and Perinatal Depression and Anxiety.Journal of obstetric, gynecologic, and neonatal nursing : JOGNN · 2021Article
- Prior Exposure to Intimate Partner Violence Associated With Less HIV Testing Among Young Women.Journal of interpersonal violence · 2021Article
- Secrecy Versus Disclosure: Women with Substance Use Disorders Share Experiences in Help Seeking During Pregnancy.Maternal and child health journal · 2020Article
- Early lessons from maternal mortality review committees on drug-related deaths-time for obstetrical providers to take the lead in addressing addiction.American journal of obstetrics & gynecology MFM · 2020Article
- Screening for Mental Health and Substance Use Disorders in Obstetric Settings.Current psychiatry reports · 2020Review
- Medications for opioid use disorder in pregnancy in a state women's prison facility.Drug and alcohol dependence · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 8 institutions in 1 country.
Funding
Abstract
We review clinical care issues that are related to illicit and therapeutic opioid use among pregnant women and women in the postpartum period and outline the major responsibilities of obstetrics providers who care for these patients during the antepartum, intrapartum, and postpartum periods. Selected patient treatment issues are highlighted, and case examples are provided. Securing a strong rapport and trust with these patients is crucial for success in delivering high-quality obstetric care and in coordinating services with other specialists as needed. Obstetrics providers have an ethical obligation to screen, assess, and provide brief interventions and referral to specialized treatment for patients with drug use disorders. Opioid-dependent pregnant women often can be treated effectively with methadone or buprenorphine. These medications are classified as pregnancy category C medications by the Food and Drug Administration, and their use in the treatment of opioid-dependent pregnant patients should not be considered "off-label." Except in rare special circumstances, medication-assisted withdrawal during pregnancy should be discouraged because of a high relapse rate. Acute pain management in this population deserves special consideration because patients who use opioids can be hypersensitive to pain and because the use of mixed opioid-agonist/antagonists can precipitate opioid withdrawal. In the absence of other indications, pregnant women who use opioids do not require more intense medical care than other pregnant patients to ensure adequate treatment and the best possible outcomes. Together with specialists in pain and addiction medicine, obstetricians can coordinate comprehensive care for pregnant women who use opioids and women who use opioids in the postpartum period.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.