Trial reportDrug and alcohol dependence2014
The influence of depressive symptoms on alcohol use among HIV-infected Russian drinkers.
Trial report in Drug and alcohol dependence, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.
- Psychological interventions for co-occurring depression and substance use disorders.The Cochrane database of systematic reviews · 2019Pooled it
- Behavioral Interventions Targeting Alcohol Use Among People Living with HIV/AIDS: A Systematic Review and Meta-Analysis.AIDS and behavior · 2017Pooled it
- Longitudinal Analysis of Depressive Symptoms, Perceived Social Support, and Alcohol Use among HIV-Infected Men Who Inject Drugs in Northern Vietnam.Substance use & misuse · 2020Trial
- HIV-related Stigma and Alcohol Involvement Among People with HIV Who Engage in Unhealthy Drinking.AIDS and behavior · 2026Article
- Depression and anxiety among people living with HIV and key populations at risk for HIV in the Eastern European and Central Asian region: a scoping review.BMJ public health · 2025Article
- Longitudinal trajectories of depressive symptoms among alcohol consuming men with HIV in India.Journal of affective disorders · 2024Article
- The Role of Alcohol-Related Behavioral Research in the Design of HIV Secondary Prevention Interventions in the Era of Antiretroviral Therapy: Targeted Research Priorities Moving Forward.AIDS and behavior · 2021Article
- Symptoms of generalized anxiety disorder as a risk factor for substance use among adults living with HIV.AIDS care · 2021Article
- Article
- Prevalence and correlates of probable depression diagnosis and suicidal ideation among patients receiving HIV care in Lilongwe, Malawi.Malawi medical journal : the journal of Medical Association of Malawi · 2018Article
- Association Between Depressive Symptom Patterns and Clinical Profiles Among Persons Living with HIV.AIDS and behavior · 2018Article
- Antiretroviral Therapy and Alcohol Interactions: X-raying Testicular and Seminal Parameters Under the HAART Era.European journal of drug metabolism and pharmacokinetics · 2018Review
- HIV Patients' Preference for Integrated Models of Addiction and HIV Treatment in Vietnam.Journal of substance abuse treatment · 2016Article
- Heroin Use and HIV Disease Progression: Results from a Pilot Study of a Russian Cohort.AIDS and behavior · 2015Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundDepressive symptoms have been linked to HIV progression through a number of biobehavioral mechanisms including increased alcohol use. Although research supports an association between alcohol use and depressive symptoms among HIV patients, there have been few studies that have examined whether depressive symptoms predict subsequent drinking, especially among heavy drinking HIV-infected patients.
methodHeavy drinking Russian HIV-infected patients (n=700) were recruited from addiction and HIV care settings for a randomized controlled trial of a risk reduction intervention [HERMITAGE]. GEE overdispersed Poisson regression analyses were conducted to assess the association between depressive symptoms and alcohol consumption 6-months later.
resultsIn adjusted analyses, depressive symptom severity was significantly associated with drinks per day (global p=.02). Compared to the non-depressed category, mild depressive symptoms were significantly associated with more drinks per day [IRR=1.55, (95% CI: 1.14, 2.09)], while moderate [IRR=1.14, (95% CI: 0.83, 1.56)] and severe [IRR=1.48, (95% CI: 0.93, 2.34)] depressive symptoms were not. Associations between depressive symptom severity and heavy drinking days were not statistically significant (global p=.19). Secondary analyses using the BDI-II screening threshold (BDI-II>14) and the BDI-II cognitive subscale suggested an association between depressive symptoms and drinks per day over time but not heavy episodic drinking.
conclusionsAmong heavy drinking HIV-infected patients, elevated depressive symptoms were associated with greater subsequent alcohol use. These findings suggest that depressive symptoms may be important to address in efforts to reduce alcohol-related risks among HIV-infected populations.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.