Evidence map›Paper›PMID 24120589›Full record

Trial reportBlood transfusion = Trasfusione del sangue2014

Autologous re-transfusion drain compared with no drain in total knee arthroplasty: a randomised controlled trial.

Wieger Horstmann, Bart Kuipers, David Ohanis, Robert Slappendel, Boudewijn Kollen, Cees Verheyen

Abstract readComparative StudyMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Blood transfusion = Trasfusione del sangue, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 5 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 5 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Platelet-rich plasma for the reduction of blood loss after total knee arthroplasty: a clinical trial.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2016
    Trial
  7. Review
  8. Article
  9. Article
  10. No benefit of autologous transfusion drains in total knee arthroplasty.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2018
    Article
  11. Review
  12. Do autologous blood transfusion systems reduce allogeneic blood transfusion in total knee arthroplasty?Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2017
    Review
  13. Major abdominal surgery in Jehovah's Witnesses.Annals of the Royal College of Surgeons of England · 2016
    Review
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Wieger HorstmannKennemer Gasthuis, Haarlem, The Netherlands.
Bart KuipersIsala Clinics, Zwolle, The Netherlands.
David OhanisIsala Clinics, Zwolle, The Netherlands.
Robert SlappendelDepartment of Quality and Safety, Amphia Hospital, Breda, The Netherlands.
Boudewijn KollenDepartment of General Practice, University Medical Center Groningen, University of Groningen, The Netherlands.
Cees VerheyenIsala Clinics, Zwolle, The Netherlands.
Isala · NLAmphia Ziekenhuis · NLSpaarne Gasthuis · NLUniversity Medical Center Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPost-operative anaemia following total knee arthroplasty is reported to impede functional mobility in the early period following surgery, whereas allogeneic blood transfusions, used to correct low post-operative haemoglobin levels, have concomitant disadvantages. The use of a post-operative autologous blood re-transfusion drainage system as well as no drainage system following total knee arthroplasty have been shown to reduce peri-operative blood loss and allogeneic blood transfusions, compared to the regularly used closed-suction drains. No randomised studies have been performed, to the best of our knowledge, that indicate the superiority of either method. MATERIALS AND

methodsAn open, randomised controlled study was conducted in 115 patients undergoing total knee arthroplasty who were randomly allocated to an autotransfusion drain or no drainage system. The primary end-point was haemoglobin level on the first post-operative day.

resultsIn the autotransfusion group 515 mL (0-1,500 mL) of drained blood was re-transfused within the first 6 hours after surgery. Haemoglobin levels on the first (11.6 vs 11.0 g/dL), second (11.0 vs 10.3 g/dL) and third (10.5 vs 9.8 g/dL) days after surgery were significantly higher in the autotransfusion group. Total peri-operative net blood loss (1,576 mL vs 1,837 mL; -P=0.03) and allogeneic transfusion rates (10.2% vs 19.6%; P=0.15) were lower in the autotransfusion group. There were no differences in pain scores, range of motion or adverse events during hospital stay and the first 3 months after surgery. DISCUSSION: Compared with no drainage, the use of a post-operative autologous blood re-transfusion drainage system following total knee arthroplasty results in higher post-operative haemoglobin levels and less total blood loss.

Indexed as

Arthroplasty, Replacement, KneeAgedAnemiaBlood Loss, SurgicalBlood TransfusionDrainageEquipment DesignFemaleHematomaHemoglobinsHumansMaleMiddle AgedOperative Blood SalvagePostoperative CarePostoperative ComplicationsHemoglobins

Identifiers

PMID24120589
PMCPMC3934246
OpenAlexW2113091670

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.