ArticlePsychiatry research2014
Impaired context processing as a potential marker of psychosis risk state.
Article in Psychiatry research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
25 citing papers in PubMed, 50 citations in OpenAlex.
- Bipolar Disorder Psychosis Risk Predicts Cue Discrimination on the AX-Continuous Performance Task Paradigm.Bipolar disorders · 2026Article
- Altered Associations Between Task Performance and Dorsolateral Prefrontal Cortex Activation During Cognitive Control in Schizophrenia.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2023Article
- Comparing the functional neuroanatomy of proactive and reactive control between patients with schizophrenia and healthy controls.Cognitive, affective & behavioral neuroscience · 2023Article
- Mechanisms underlying dorsolateral prefrontal cortex contributions to cognitive dysfunction in schizophrenia.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022Review
- Neural, behavioural and real-life correlates of social context sensitivity and social reward learning during interpersonal interactions in the schizophrenia spectrum.The Australian and New Zealand journal of psychiatry · 2022Article
- Task-related neural mechanisms of persecutory ideation in schizophrenia and community monozygotic twin-pairs.Human brain mapping · 2021Article
- Comparing machine and deep learning-based algorithms for prediction of clinical improvement in psychosis with functional magnetic resonance imaging.Human brain mapping · 2021Article
- Differing functional mechanisms underlie cognitive control deficits in psychotic spectrum disorders.Journal of psychiatry & neuroscience : JPN · 2020Article
- Adolescents at clinical high risk for psychosis show qualitatively altered patterns of activation during rule learning.NeuroImage. Clinical · 2020Article
- Common Data Elements for National Institute of Mental Health-Funded Translational Early Psychosis Research.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2020Review
- Baseline Frontoparietal Task-Related BOLD Activity as a Predictor of Improvement in Clinical Symptoms at 1-Year Follow-Up in Recent-Onset Psychosis.The American journal of psychiatry · 2019Article
- Functional deficits in attenuated psychosis syndrome and related conditions: Current and future treatment options.Schizophrenia research. Cognition · 2019Review
- Should I Stay or Should I Go? FMRI Study of Response Inhibition in Early Illness Schizophrenia and Risk for Psychosis.Schizophrenia bulletin · 2019Article
- Association of Age at Onset and Longitudinal Course of Prefrontal Function in Youth With Schizophrenia.JAMA psychiatry · 2018Article
- Longitudinal stability of cognitive control in early psychosis: Nondegenerative deficits across diagnoses.Journal of abnormal psychology · 2018Article
- Staged Treatment in Early Psychosis: A sequential multiple assignment randomised trial of interventions for ultra high risk of psychosis patients.Early intervention in psychiatry · 2018Article
- Levels of Cognitive Control: A Functional Magnetic Resonance Imaging-Based Test of an RDoC Domain Across Bipolar Disorder and Schizophrenia.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2018Article
- Article
- Aberrant Temporal Connectivity in Persons at Clinical High Risk for Psychosis.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2017Article
- Episodic memory functions in first episode psychosis and clinical high risk individuals.Schizophrenia research · 2017Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
While structural abnormalities of the dorsolateral prefrontal cortex (DLPFC) may pre-date and predict psychosis onset, the relationships between functional deficits, cognitive and psychosocial impairments has yet to be explored in the at-risk period. An established measure of cognitive control (AXCPT) was administered to demographically matched clinical-high-risk (CHR; n=25), first-episode schizophrenia (FE; n=35), and healthy control (HC; n=35) participants during functional magnetic resonance imaging (fMRI) to investigate these relationships. CHR and FE individuals demonstrated impaired context processing and reduced DLPFC activation relative to HC individuals during increased cognitive control demands. FE and CHR individuals' ability to increase DLPFC activity in response to cognitive control demands was associated with better task performance. Task performance was also associated with severity of disorganization and poverty symptoms in FE participants. These findings support more extensive studies using fMRI to examine the clinical significance of prefrontal cortical functioning in the earliest stages of psychosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.