Evidence map›Paper›PMID 24119221›Full record

ArticleClinical & experimental ophthalmology2014

Comparison of anterior segment morphology following prophylactic laser peripheral iridotomy in Caucasian and Chinese eyes.

Roland Y Lee, Toshimitsu Kasuga, Qi N Cui, Guofu Huang, Mingguang He, Shan C Lin

Abstract readComparative Study
In one paragraph

Article in Clinical & experimental ophthalmology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Roland Y LeeDepartment of Ophthalmology, University of California, San Francisco, California, USA.
Toshimitsu Kasuga
Qi N Cui
Guofu Huang
Mingguang He
Shan C Lin
University of California, San Francisco · USJuntendo University · JP

Funding

Rapid-Prototyping and Design CoreP30EY002162 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LAKKARAJU, APARNA · 1985 to 2024
$16.8M
NEI NIH HHS EY002162NEI NIH HHS P30 EY002162
6 · The paper itself

Abstract

backgroundTo compare anterior segment biometric parameters between Caucasians and Chinese before and after laser peripheral iridotomy.

designProspective clinical cohort study.

participantsCaucasian and Chinese primary angle-closure suspects.

methodsAnterior segment optical coherence tomography images captured before and after laser peripheral iridotomy were analysed to measure anterior segment biometric parameters. Paired Student's t-tests were used for within-ethnic group comparisons. Univariate and linear mixed-effect regression models were used for between-ethnic group comparisons.

main outcome measuresAngle opening distance, angle recess area, iris thickness, iris curvature, anterior chamber area, anterior chamber volume and anterior chamber width.

resultsCaucasians had significantly greater preoperative angle recess area, anterior chamber width, and iris curvature and lower preoperative iris thickness compared to Chinese (P < 0.05). Significant postoperative increases in angle opening distance, angle recess area, anterior chamber area, anterior chamber volume, and anterior chamber width along with significant postoperative decrease in iris curvature were observed within both ethnic groups (P < 0.05). However, the amount of laser peripheral iridotomy-induced changes in angle opening distance, angle recess area, anterior chamber area, anterior chamber volume, anterior chamber width, and iris curvature did not differ between the two ethnic groups (P < 0.05).

conclusionBoth Caucasian and Chinese demonstrated opening of anterior chamber angle width, expansion of anterior chamber dimensions, and flattening of iris convexity after laser peripheral iridotomy. Although certain aspects of anterior segment anatomy differed between Caucasians and Chinese preoperatively, they did not translate into significant ethnic differences in the amount of laser peripheral iridotomy-induced changes in the anterior segment biometric parameters.

Indexed as

AgedAnterior Eye SegmentAsian PeopleBiometryChinaFemaleGlaucoma, Angle-ClosureGonioscopyHumansIntraocular PressureIridectomyIrisLaser TherapyMaleMiddle AgedProspective Studiesangle closureanterior segment optical coherence tomographyethnicityglaucomalaser peripheral iridotomy

Identifiers

PMID24119221
PMCPMC3975703
OpenAlexW2138849279

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.