Evidence map›Paper›PMID 24118802›Full record

ArticleJournal of applied microbiology2014

Synthetic brominated furanone F202 prevents biofilm formation by potentially human pathogenic Escherichia coli O103:H2 and Salmonella ser. Agona on abiotic surfaces.

L K Vestby, K C S Johannesen, I L Witsø, O Habimana, A A Scheie, A M Urdahl, T Benneche, S Langsrud, L L Nesse

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of applied microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Furanone and phytol influence metabolic phenotypes regulated by acyl-homoserine lactone in Salmonella.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022
    Article
  3. A Brominated Furanone InhibitsBiomedicines · 2022
    Article
  4. Article
  5. Article
  6. Efficacy of Synthetic Furanones onFoods (Basel, Switzerland) · 2019
    Article
  7. Review
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

L K VestbyNorwegian Veterinary Institute, Department of Laboratory Services, Section for Bacteriology- aquatic and terrestrial, Oslo, Norway.
K C S JohannesenNorwegian Veterinary Institute, Department of Laboratory Services, Section for Bacteriology- aquatic and terrestrial, Oslo, Norway.
I L WitsøFaculty of Dentistry, Department of Oral Biology, University of Oslo, Oslo, Norway.
O HabimanaNofima, Aas, Norway.
A A ScheieFaculty of Dentistry, Department of Oral Biology, University of Oslo, Oslo, Norway.
A M UrdahlNorwegian Veterinary Institute, Department of Health Surveillance, Section for Veterinary Public Health, Oslo, Norway.
T BennecheFaculty of Mathematics and Natural Sciences, Department of Chemistry, University of Oslo, Oslo, Norway.
S LangsrudNofima, Aas, Norway.
L L NesseNorwegian Veterinary Institute, Department of Laboratory Services, Section for Bacteriology- aquatic and terrestrial, Oslo, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsInvestigate the use of a synthetic brominated furanone (F202) against the establishment of biofilm by Salmonella ser. Agona and E. coli O103:H2 under temperature conditions relevant for the food and feed industry as well as under temperature conditions optimum for growth. METHODS AND

resultsEffect of F202 on biofilm formation by Salmonella ser. Agona and E. coli O103:H2 was evaluated using a microtiter plate assay and confocal microscopy. Effect of F202 on bacterial motility was investigated using swimming and swarming assays. Influence on flagellar synthesis by F202 was examined by flagellar staining. Results showed that F202 inhibited biofilm formation without being bactericidal. F202 was found to affect both swimming and swarming motility without, however, affecting the expression of flagella.

conclusionsF202 showed its potential as a biofilm inhibitor of Salmonella ser. Agona and E. coli O103:H2 under temperature conditions relevant for the feed and food industry as well as temperatures optimum for growth. One potential mode of action of F202 was found to be by targeting flagellar function. SIGNIFICANCE AND IMPACT OF THE STUDY: The present study gives valuable new knowledge to the potential use of furanones as a tool in biofilm management in the food and feed industry.

Indexed as

4-ButyrolactoneAnti-Bacterial AgentsBiofilmsEscherichia coliFlagellaFood-Processing IndustryFuransHalogenationHumansMicroscopy, ConfocalMovementSalmonella4-Butyrolactone5-bromomethylene-2(5H)-furanoneAnti-Bacterial AgentsFuransbiofilmsE. coli (all potentially pathogenic types)food safetySalmonella

Identifiers

PMID24118802
PMCPMC4255294

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.