Evidence map›Paper›PMID 24118292›Full record

ArticleAddiction (Abingdon, England)2014

Psychiatric comorbidity in treatment-seeking substance use disorder patients with and without attention deficit hyperactivity disorder: results of the IASP study.

Katelijne van Emmerik-van Oortmerssen, Geurt van de Glind, Maarten W J Koeter, Steve Allsop, Marc Auriacombe, Csaba Barta, Eli Torild H Bu, Yuliya Burren, Pieter-Jan Carpentier, Susan Carruthers and 20 more

Abstract readMulticenter Study
In one paragraph

Article in Addiction (Abingdon, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 4 pooled it
8.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 4 syntheses or guidelines pooled it, 163 citations in OpenAlex.

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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors at 19 institutions in 10 countries.

Katelijne van Emmerik-van OortmerssenArkin Mental Health and Addiction Treatment Center, Amsterdam, the Netherlands; Amsterdam Institute for Addiction Research, Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands; Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
Geurt van de Glind
Maarten W J Koeter
Steve Allsop
Marc Auriacombe
Csaba Barta
Eli Torild H Bu
Yuliya Burren
Pieter-Jan Carpentier
Susan Carruthers
Miguel Casas
Zsolt Demetrovics
Geert Dom
Stephen V Faraone
Melina Fatseas
Johan Franck
Brian Johnson
Máté Kapitány-Fövény
Sharlene Kaye
Maija Konstenius
Frances R Levin
Franz Moggi
Merete Møller
J Antoni Ramos-Quiroga
Arild Schillinger
Arvid Skutle
Sofie Verspreet
IASP research group
Wim van den Brink
Robert A Schoevers
University of Amsterdam · NLCurtin University · AUKarolinska Institutet · SEØstfold Hospital Trust · NOSUNY Upstate Medical University · USUniversité de Bordeaux · FRUniversity of Antwerp · BECentro de Investigación Biomédica en Red de Salud Mental · ESColumbia University · USEötvös Loránd University · HUNational Institute of Menthal Health, Neurology and Neurosurgery - Nyírő Gyula Hospital · HUReinier van Arkel · NLSemmelweis University · HUUniversitat Autònoma de Barcelona · ESUniversity Hospital of Bern · CHUniversity Medical Center Groningen · NLUniversity of Fribourg · CHUniversity of Groningen · NLUNSW Sydney · AU

Funding

Substance Abuse Treatment Development and Clinical Research MentoringK24DA029647 · NIDA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LEVIN, FRANCES RUDNICK · 2010 to 2019
$1.8M
NIDA NIH HHS K24 DA029647
6 · The paper itself

Abstract

aimsTo determine comorbidity patterns in treatment-seeking substance use disorder (SUD) patients with and without adult attention deficit hyperactivity disorder (ADHD), with an emphasis on subgroups defined by ADHD subtype, taking into account differences related to gender and primary substance of abuse.

designData were obtained from the cross-sectional International ADHD in Substance use disorder Prevalence (IASP) study.

settingForty-seven centres of SUD treatment in 10 countries.

participantsA total of 1205 treatment-seeking SUD patients. MEASUREMENTS: Structured diagnostic assessments were used for all disorders: presence of ADHD was assessed with the Conners' Adult ADHD Diagnostic Interview for DSM-IV (CAADID), the presence of antisocial personality disorder (ASPD), major depression (MD) and (hypo)manic episode (HME) was assessed with the Mini International Neuropsychiatric Interview-Plus (MINI Plus), and the presence of borderline personality disorder (BPD) was assessed with the Structured Clinical Interview for DSM-IV Axis II (SCID II).

findingsThe prevalence of DSM-IV adult ADHD in this SUD sample was 13.9%. ASPD [odds ratio (OR) = 2.8, 95% confidence interval (CI) = 1.8-4.2], BPD (OR = 7.0, 95% CI = 3.1-15.6 for alcohol; OR = 3.4, 95% CI = 1.8-6.4 for drugs), MD in patients with alcohol as primary substance of abuse (OR = 4.1, 95% CI = 2.1-7.8) and HME (OR = 4.3, 95% CI = 2.1-8.7) were all more prevalent in ADHD(+) compared with ADHD(-) patients (P < 0.001). These results also indicate increased levels of BPD and MD for alcohol compared with drugs as primary substance of abuse. Comorbidity patterns differed between ADHD subtypes with increased MD in the inattentive and combined subtype (P < 0.01), increased HME and ASPD in the hyperactive/impulsive (P < 0.01) and combined subtypes (P < 0.001) and increased BPD in all subtypes (P < 0.001) compared with SUD patients without ADHD. Seventy-five per cent of ADHD patients had at least one additional comorbid disorder compared with 37% of SUD patients without ADHD.

conclusionsTreatment-seeking substance use disorder patients with attention deficit hyperactivity disorder are at a very high risk for additional externalizing disorders.

Indexed as

AdolescentAdultAgedAttention Deficit Disorder with HyperactivityBipolar DisorderCross-Sectional StudiesDepressive DisorderDiagnosis, Dual (Psychiatry)FemaleHumansMaleMiddle AgedPatient Acceptance of Health CarePersonality DisordersPsychiatric Status Rating ScalesRisk FactorsADHDantisocial personality disorderbipolar disorderborderline personality disordercomorbiditydepressionsubstance use disorder

Identifiers

PMID24118292
PMCPMC4112562
OpenAlexW2097847682

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.