Evidence map›Paper›PMID 24118276›Full record

ReviewExperimental dermatology2013

Gentian violet: a 19th century drug re-emerges in the 21st century.

Alexander M Maley, Jack L Arbiser

Open access · greenAbstract readHistorical ArticleReview
In one paragraph

Review in Experimental dermatology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 1 synthesis or guideline pooled it, 149 citations in OpenAlex.

  1. Pooled it
  2. State-of-the-Art Review: Managing Vulvovaginal Candidiasis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Review
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  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Production of biochar fromBioengineered · 2023
    Article
  14. Review
  15. Diagnosis of traumatic shoulder arthrotomies using saline load test with intra-articular pressure monitoring.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2023
    Article
  16. Article
  17. Pathogens and global health · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Alexander M MaleyDepartment of Dermatology, Emory University School of Medicine, Atlanta, GA, USA; Atlanta Veterans Administration Hospital, Atlanta, GA, USA.
Jack L Arbiser
Emory University · US

Funding

Cutaneous Hemangiomas and Signal TransductionR01AR047901 · NIAMS · EMORY UNIVERSITY · PI ARBISER, JACK L · 2001 to 2018
$4.3M
UV light and the cutaneous neurosensory systemP30AR042687 · NIAMS · EMORY UNIVERSITY · PI CAUGHMAN, STEWART W · 1994 to 2003
$2.5M
NIAMS NIH HHS P30 AR042687NIAMS NIH HHS P30 AR42687NIAMS NIH HHS R01 AR047901NIAMS NIH HHS R01 AR47901
6 · The paper itself

Abstract

Gentian violet (GV) has a long and varied history as a medicinal agent. Historically used as an antibacterial and antifungal, recent reports have shown its utility as an antitypranosomal, antiviral and anti-angiogenic agent. The objective of this article is to summarize evidence regarding the efficacy and safety of GV use in dermatology. Recent discoveries have found novel targets of GV, namely NADPH oxidase in mammalian cells and thioredoxin reductase 2 in bacterial, fungal and parasitic cells. These discoveries have expanded the use of GV in the 21st century. Given that GV is well tolerated, effective and inexpensive, its use in dermatology is predicted to increase.

Indexed as

Anti-Infective AgentsAnti-Infective Agents, LocalAntineoplastic AgentsDermatologyGentian VioletHistory, 19th CenturyHumansMethicillin-Resistant Staphylococcus aureusPlant ExtractsSkin DiseasesStaphylococcal InfectionsAnti-Infective AgentsAnti-Infective Agents, LocalAntineoplastic AgentsGentian VioletPlant Extractscrystal violetGentian Violettriphenylmethane dye

Identifiers

PMID24118276
PMCPMC4396813
OpenAlexW2034715647

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.