Evidence map›Paper›PMID 24117816›Full record

ReviewImmunological reviews2013

The role of the cytoskeleton at the immunological synapse.

Alex T Ritter, Karen L Angus, Gillian M Griffiths

Open access · hybridAbstract readReview
In one paragraph

Review in Immunological reviews, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 120 citations in OpenAlex.

  1. Risk variants disrupting enhancers of TProceedings of the National Academy of Sciences of the United States of America · 2019
    Trial
  2. Article
  3. Review
  4. Review
  5. HIV Nef amplifies mechanical heterogeneity to promote immune evasion.bioRxiv : the preprint server for biology · 2025
    Article
  6. Review
  7. Article
  8. Review
  9. Imaging actin organisation and dynamics in 3D.Journal of cell science · 2024
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Alex T RitterCambridge Institute for Medical Research, University of Cambridge Biomedical Campus, Cambridge, UK.
Karen L Angus
Gillian M Griffiths
National Institute for Health Research · GBUniversity of Cambridge · GB

Funding

Wellcome Trust 075880Wellcome Trust 100140
6 · The paper itself

Abstract

It has been over 30 years since the reorganization of both the microtubule network and a 'peculiar actin polarization' was reported at the contact area of cytotoxic T lymphocytes interacting with target cells. Since that time, hundreds of studies have been published in an effort to elucidate the structure and function of the microtubule network and the actin cytoskeleton in T-cell activation, migration, and effector function at the interface between a T cell and its cognate antigen-presenting cell or target cell. This interface has become known as the immunological synapse, and this review examines some of the roles played by the cytoskeleton at the synapse.

Indexed as

ActinsAnimalsCalcium SignalingCell MovementCentrosomeCytoskeletonDyneinsHumansImmunological SynapsesLymphocyte ActivationMicrotubulesT-LymphocytesActinsDyneinscytoskeletonsynapseT lymphocytes

Identifiers

PMID24117816
PMCPMC4312978
OpenAlexW2008471079

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.