Evidence map›Paper›PMID 24116132›Full record

ArticlePloS one2013

Acceptability of pre-exposure prophylaxis among men who have sex with men and transgender women in Northern Thailand.

Daniel Yang, Chonlisa Chariyalertsak, Antika Wongthanee, Surinda Kawichai, Kriengkrai Yotruean, Pongpun Saokhieo, Thomas Guadamuz, Voravit Suwanvanichkij, Chris Beyrer, Suwat Chariyalertsak

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 3 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 3 syntheses or guidelines pooled it, 79 citations in OpenAlex.

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  19. Characterizing PrEP Awareness and Interest Among Filipina Transgender Women.AIDS education and prevention : official publication of the International Society for AIDS Education · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Daniel YangUniversity of California San Francisco, San Francisco, California, United States of America ; Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.
Chonlisa Chariyalertsak
Antika Wongthanee
Surinda Kawichai
Kriengkrai Yotruean
Pongpun Saokhieo
Thomas Guadamuz
Voravit Suwanvanichkij
Chris Beyrer
Suwat Chariyalertsak
Chiang Mai University · THJohns Hopkins University · USMinistry of Public Health · THMahidol University · THUniversity of California, San Francisco · US

Funding

Fogarty International Clinical Research Scholars Support Center @ Vanderbilt-AAMCR24TW007988 · FIC · VANDERBILT UNIVERSITY · PI VERMUND, STEN H. · 2007 to 2011
$27.6M
TUBERCULOSIS INTERNATIONAL TRAINING AND RESEARCH PROGRAMD43TW000010 · FIC · JOHNS HOPKINS UNIVERSITY · PI BEYRER, CHRISTOPHER C. · 1988 to 2012
$19.8M
Developing a Community Level Behavioral Intervention for MSM in ThailandK01MH085567 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GUADAMUZ, THOMAS E · 2009 to 2013
$817k
FIC NIH HHS D43 TW000010FIC NIH HHS D43 TW00010-22FIC NIH HHS R24 TW007988NIMH NIH HHS K01 MH085567
6 · The paper itself

Abstract

backgroundNorthern Thailand has a high burden HIV epidemic among MSM and TG. Oral pre-exposure prophylaxis (PrEP) with tenofovir-emtricitabine has demonstrated efficacy in preventing HIV among MSM and TG in Chiang Mai, Thailand. Determinants of PrEP acceptability are needed to gauge the potential uptake of this prevention strategy.

methodsFrom January to February 2012, 238 MSM and TG participants, who self-reported as HIV-uninfected or of unknown status, completed a self-administered survey on hand-held computers. Participants were recruited by venue-day-time sampling and asked to rate their likelihood of using oral PrEP for HIV prevention with an efficacy of 50%. PrEP acceptability was defined as being "very likely" to use PrEP. Odds ratios and 95% CIs were calculated to identify correlates of acceptability.

results131 MSM and 107 TG responded, with mean ages of 23.7 and 21.8, respectively. 24% of MSM engaged primarily in receptive anal sex vs. 74% of TG. 21% of MSM and 44% of TG reported regular medication use. Prior awareness of PrEP was high at 66% among both MSM and TG respondents. 41% of MSM and 37% of TG were "very likely" to use PrEP. Among MSM, factors associated with PrEP acceptability included a prior history of STIs (AOR 4.6; 95%CIs 1.7-12.6), previous HIV testing (AOR 2.4 95%CIs 1.1-5.3), regularly planned sex (AOR 2.8 95%CIs 1.1-7.2), and infrequent sex (AOR 2.9 95%CIs 1.3-6.3). Among TG, factors associated with acceptability included prior awareness of PrEP (AOR 3.3; 95%CIs 1.2-9.0) and having private insurance (AOR 5.0; 95%CIs 1.3-19.0).

conclusionMSM and TG in Northern Thailand are distinct groups in terms of sexual behaviors, patterns of medication use, and correlates of PrEP acceptability. Efforts to maximize PrEP uptake should include expanded HIV testing services and the provision of financial subsidies to reduce the cost of PrEP.

Indexed as

AdenineAdministration, OralAdolescentAdultAnti-HIV AgentsFemaleHIV InfectionsHomosexuality, MaleHumansMaleMiddle AgedMultivariate AnalysisOrganophosphonatesOutcome Assessment, Health CarePatient Acceptance of Health CareSelf ReportAdenineAnti-HIV AgentsOrganophosphonatesTenofovir

Identifiers

PMID24116132
PMCPMC3792988
OpenAlexW2068158763

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.