Evidence map›Paper›PMID 24115597›Full record

Trial reportJournal of magnetic resonance imaging : JMRI2014

Fully automated tool to identify the aorta and compute flow using phase-contrast MRI: validation and application in a large population based study.

Akshay Goel, Roderick McColl, Kevin S King, Anthony Whittemore, Ronald M Peshock

Abstract readRandomized Controlled TrialValidation Study
In one paragraph

Trial report in Journal of magnetic resonance imaging : JMRI, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Automated quantification of myocardial tissue characteristics from native TJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2020
    Article
  5. Article
  6. Article
  7. Quantification of aortic pulse wave velocity from a population based cohort: a fully automatic method.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2019
    Article
  8. Automated analysis of cardiovascular magnetic resonance myocardial native TJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2019
    Article
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Akshay GoelDepartment of Radiology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA.
Roderick McColl
Kevin S King
Anthony Whittemore
Ronald M Peshock

Funding

UT Southwestern Center for Translational Medicine (UL1/KL2/TL1)UL1TR001105 · NCATS · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2013 to 2017
$24.5M
UT-Southwestern Clinical and Translational Alliance for Research (UT-STAR) (TL1)UL1TR000451 · NCATS · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2012 to 2012
$6.3M
UT Southwestern Center for Translational Medicine (UL1/KL2/TL1KL2TR001103 · NCATS · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2013 to 2017
$4.0M
NCATS NIH HHS KL2 TR001103NCATS NIH HHS UL1 TR000451NCATS NIH HHS UL1TR000451NCATS NIH HHS UL1 TR001105
6 · The paper itself

Abstract

purposeTo assess if fully automated localization of the aorta can be achieved using phase contrast (PC) MR images. MATERIALS AND

methodsPC cardiac-gated MR images were obtained as part of a large population-based study. A fully automated process using the Hough transform was developed to localize the ascending aorta (AAo) and descending aorta (DAo). The study was designed to validate this technique by determining: (i) its performance in localizing the AAo and DAo; (ii) its accuracy in generating AAo flow volume and DAo flow volume; and (iii) its robustness on studies with pathological abnormalities or imaging artifacts.

resultsThe algorithm was applied successfully on 1884 participants. In the randomly selected 50-study validation set, linear regression shows an excellent correlation between the automated (A) and manual (M) methods for AAo flow (r = 0.99) and DAo flow (r = 0.99). Bland-Altman difference analysis demonstrates strong agreement with minimal bias for: AAo flow (mean difference [A-M] = 0.47 ± 2.53 mL), and DAo flow (mean difference [A-M] = 1.74 ± 2.47 mL).

conclusionA robust fully automated tool to localize the aorta and provide flow volume measurements on phase contrast MRI was validated on a large population-based study.

Indexed as

AlgorithmsAortaAortographyBlood Flow VelocityBlood VolumeBlood Volume DeterminationCardiac-Gated Imaging TechniquesFemaleHumansImage EnhancementImage Interpretation, Computer-AssistedMagnetic Resonance AngiographyMaleMiddle AgedReproducibility of ResultsSensitivity and Specificityaortaautomaticlocalizationphase contrastsegmentation

Identifiers

PMID24115597
PMCPMC3969872

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.