Evidence map›Paper›PMID 24115554›Full record

ArticleJournal of magnetic resonance imaging : JMRI2014

MRI of the hip at 7T: feasibility of bone microarchitecture, high-resolution cartilage, and clinical imaging.

Gregory Chang, Cem M Deniz, Stephen Honig, Kenneth Egol, Ravinder R Regatte, Yudong Zhu, Daniel K Sodickson, Ryan Brown

Open access · bronzeAbstract read
In one paragraph

Article in Journal of magnetic resonance imaging : JMRI, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 42 citations in OpenAlex.

  1. A CombinedAnnals of biomedical engineering · 2026
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  5. Review
  6. The imaging evaluation of acetabular labral lesions.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2021
    Review
  7. Musculoskeletal MR Imaging Applications at Ultra-High (7T) Field Strength.Magnetic resonance imaging clinics of North America · 2021
    Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Investigations of Cartilage Matrix Degeneration in Patients with Early-Stage Femoral Head Necrosis.Medical science monitor : international medical journal of experimental and clinical research · 2017
    Article
  14. MRI assessment of bone structure and microarchitecture.Journal of magnetic resonance imaging : JMRI · 2017
    Review
  15. Article
  16. Advances in imaging approaches to fracture risk evaluation.Translational research : the journal of laboratory and clinical medicine · 2017
    Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Gregory ChangDepartment of Radiology, NYU Langone Medical Center, Center for Musculoskeletal Care, New York, New York, USA.
Cem M Deniz
Stephen Honig
Kenneth Egol
Ravinder R Regatte
Yudong Zhu
Daniel K Sodickson
Ryan Brown
New York University · USNew York University Langone Orthopedic Hospital · USNYU Langone Health · US

Funding

High-Performance High-Field Parallel MRI.R01EB002568 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SODICKSON, DANIEL K · 2003 to 2014
$4.8M
RF Technology Innovation for Advancing High Field MR.R01EB011551 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI COLLINS, CHRISTOPHER M · 2011 to 2014
$2.7M
Osteoarthritis: Identification of Novel Imaging Biomarkers via 23Na/1H MRI at 7 TK23AR059748 · NIAMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CHANG, GREGORY · 2011 to 2015
$663k
NIAMS NIH HHS K23 AR059748NIBIB NIH HHS R01 EB002568NIBIB NIH HHS R01 EB011551PHS HHS K23-R059748PHS HHS R01-B002568PHS HHS R01-B011551
6 · The paper itself

Abstract

purposeTo demonstrate the feasibility of performing bone microarchitecture, high-resolution cartilage, and clinical imaging of the hip at 7T. MATERIALS AND

methodsThis study had Institutional Review Board approval. Using an 8-channel coil constructed in-house, we imaged the hips of 15 subjects on a 7T magnetic resonance imaging (MRI) scanner. We applied: 1) a T1-weighted 3D fast low angle shot (3D FLASH) sequence (0.23 × 0.23 × 1-1.5 mm(3) ) for bone microarchitecture imaging; 2) T1-weighted 3D FLASH (water excitation) and volumetric interpolated breath-hold examination (VIBE) sequences (0.23 × 0.23 × 1.5 mm(3) ) with saturation or inversion recovery-based fat suppression for cartilage imaging; 3) 2D intermediate-weighted fast spin-echo (FSE) sequences without and with fat saturation (0.27 × 0.27 × 2 mm) for clinical imaging.

resultsBone microarchitecture images allowed visualization of individual trabeculae within the proximal femur. Cartilage was well visualized and fat was well suppressed on FLASH and VIBE sequences. FSE sequences allowed visualization of cartilage, the labrum (including cartilage and labral pathology), joint capsule, and tendons.

conclusionThis is the first study to demonstrate the feasibility of performing a clinically comprehensive hip MRI protocol at 7T, including high-resolution imaging of bone microarchitecture and cartilage, as well as clinical imaging.

Indexed as

Bone Diseases, MetabolicCartilage, ArticularFeasibility StudiesFemaleFemurHip JointHumansImaging, Three-DimensionalMagnetic Resonance ImagingMagneticsMaleMiddle AgedReproducibility of ResultsSensitivity and Specificity7Tbone microarchitecturecartilageclinicalhipMRI

Identifiers

PMID24115554
PMCPMC3962810
OpenAlexW2100172854

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.