Evidence map›Paper›PMID 24115478›Full record

Trial reportJournal of the American Society of Nephrology : JASN2014

Psychosocial intervention improves depression, quality of life, and fluid adherence in hemodialysis.

Daniel Cukor, Nisha Ver Halen, Deborah Rosenthal Asher, Jeremy D Coplan, Jeremy Weedon, Katarzyna E Wyka, Subodh J Saggi, Paul L Kimmel

3 registry-linked trialsAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of the American Society of Nephrology : JASN, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 98 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed, 12 pooled it
9.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00618475 nacompletednot on this map

Cognitive Behavioral Treatment of Depression in ESRD Patients on Dialysis

TypeinterventionalSponsorNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Ran2008 to 2012Enrolled65ConditionsEnd Stage Renal Disease, DepressionArmsCognitive behavioral therapy
NCT02358343 phase3completednot on this mapstarted 2015, after this paper: background citation

ASCEND: A Trial of Sertraline vs. CBT for End-stage Renal Disease Patients With Depression

TypeinterventionalSponsorUniversity of WashingtonRan2015 to 2017Enrolled184ConditionsDepression, End Stage Renal DiseaseArmsEngagement Interview, Cognitive Behavioral Therapy, Antidepressant Drug Therapy
NCT03978806 nacompletednot on this mapstarted 2020, after this paper: background citation

Fostering Resilience on Dialysis: A Peer Navigator Study to Improve the Well-being of Latinos on Hemodialysis

TypeinterventionalSponsorUniversity of Colorado, DenverRan2020 to 2024Enrolled139ConditionsRacial/Ethnic Minorities on DialysisArmsActive Comparator: peer navigator, Placebo Comparator: Control Arm (standard of care)
3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 12 syntheses or guidelines pooled it, 253 citations in OpenAlex.

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  4. Measuring quality of life in trials including patients on haemodialysis: methodological issues surrounding the use of the Kidney Disease Quality of Life Questionnaire.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2022
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38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Daniel CukorDepartments of Psychiatry and Behavioral Sciences.
Nisha Ver Halen
Deborah Rosenthal Asher
Jeremy D Coplan
Jeremy Weedon
Katarzyna E Wyka
Subodh J Saggi
Paul L Kimmel
Institute of Behavioral Sciences · JPSUNY Downstate Health Sciences University · USGeorge Washington University · USNewYork–Presbyterian Hospital · USOffice of Advanced Scientific Computing Research · US

Funding

Cognitive Behavioral Treatment of Depression in ESRD PAtients on DialysisK23DK076980 · NIDDK · SUNY DOWNSTATE MEDICAL CENTER · PI CUKOR, DANIEL · 2007 to 2011
$773k
NIDDK NIH HHS K23 DK076980NIDDK NIH HHS K23DK076980
6 · The paper itself

Abstract

Patients with ESRD have high rates of depression, which is associated with diminished quality of life and survival. We determined whether individual cognitive behavioral therapy (CBT) reduces depression in hemodialysis patients with elevated depressive affect in a randomized crossover trial. Of 65 participants enrolled from two dialysis centers in New York, 59 completed the study and were assigned to the treatment-first group (n=33) or the wait-list control group (n=26). In the intervention phase, CBT was administered chairside during dialysis treatments for 3 months; participants were assessed 3 and 6 months after randomization. Compared with the wait-list group, the treatment-first group achieved significantly larger reductions in Beck Depression Inventory II (self-reported, P=0.03) and Hamilton Depression Rating Scale (clinician-reported, P<0.001) scores after intervention. Mean scores for the treatment-first group did not change significantly at the 3-month follow-up. Among participants with depression diagnosed at baseline, 89% in the treatment-first group were not depressed at the end of treatment compared with 38% in the wait-list group (Fisher's exact test, P=0.01). Furthermore, the treatment-first group experienced greater improvements in quality of life, assessed with the Kidney Disease Quality of Life Short Form (P=0.04), and interdialytic weight gain (P=0.002) than the wait-list group, although no effect on compliance was evident at follow-up. In summary, CBT led to significant improvements in depression, quality of life, and prescription compliance in this trial, and studies should be undertaken to assess the long-term effects of CBT on morbidity and mortality in patients with ESRD.

Indexed as

Cognitive Behavioral TherapyCross-Over StudiesDepressionFemaleHumansKidney Failure, ChronicMalePatient ComplianceQuality of LifeRenal DialysisWater-Electrolyte Balance

Identifiers

PMID24115478
PMCPMC3871769
OpenAlexW2169214416

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.